DMTN and TEX11

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		DMTN	TEX11
Description		dematin actin binding protein	testis expressed 11
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Smooth Endoplasmic Reticulum Cytosol Cytoskeleton Actin Filament Plasma Membrane Endomembrane System Postsynaptic Density Spectrin-associated Cytoskeleton Actin Cytoskeleton Membrane Cortical Cytoskeleton Platelet Dense Tubular Network Membrane Cell Projection Membrane Cytoplasmic Vesicle Cell Projection Synapse Perinuclear Region Of Cytoplasm	Condensed Nuclear Chromosome Synaptonemal Complex Central Element Chromosome
	Molecular Function	Actin Binding Signaling Receptor Binding Protein Binding Spectrin Binding Actin Filament Binding	Protein Binding
	Biological Process	Cytoskeleton Organization Regulation Of Cell Shape Regulation Of Lamellipodium Assembly Positive Regulation Of Fibroblast Migration Negative Regulation Of Peptidyl-threonine Phosphorylation Negative Regulation Of Cell-substrate Adhesion Lamellipodium Assembly Actin Cytoskeleton Organization Regulation Of Actin Cytoskeleton Organization Negative Regulation Of Peptidyl-serine Phosphorylation Erythrocyte Development Negative Regulation Of Peptidyl-tyrosine Phosphorylation Actin Filament Bundle Assembly Regulation Of Filopodium Assembly Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Actin Filament Capping Negative Regulation Of Focal Adhesion Assembly Protein-containing Complex Assembly Cellular Response To CAMP Endoplasmic Reticulum Tubular Network Organization Positive Regulation Of Wound Healing Negative Regulation Of Protein Targeting To Membrane Negative Regulation Of Substrate Adhesion-dependent Cell Spreading	Resolution Of Meiotic Recombination Intermediates Meiotic Gene Conversion Apoptotic Process Male Meiosis Chromosome Segregation Synaptonemal Complex Assembly Reciprocal Meiotic Recombination Male Meiotic Nuclear Division Male Gonad Development Fertilization Ectopic Germ Cell Programmed Cell Death Negative Regulation Of Apoptotic Process Chiasma Assembly Negative Regulation Of Developmental Process Meiotic Cell Cycle Negative Regulation Of Reproductive Process
Pathways		Miscellaneous transport and binding events
Drugs
Diseases
GWAS		Alanine aminotransferase levels ( 33547301) Apolipoprotein B levels ( 32203549) Gamma glutamyl transferase levels ( 33339817) LDL cholesterol ( 30275531) LDL cholesterol levels ( 32203549) Liver enzyme levels (alanine transaminase) ( 33972514) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Low density lipoprotein cholesterol levels ( 32154731) Total cholesterol levels ( 30275531)	Mean corpuscular volume ( 29403010) Waist circumference ( 28552196)
Interacting Genes		16 interacting genes: ACTB ACTC1 APP CEP76 DYNC1LI2 EPB42 GOLGA2 NEDD4L PRKACA PROCR PTOV1 SNCA SNRPD2 SPTB TEX11 TRAF2	92 interacting genes: ATXN3 BCL2L2 BEX1 BORCS8 BORCS8-MEF2B BRMS1L CATSPERT CBY2 CCDC198 CCND2 CCND3 CD74 CDKN1A CDKN2D CENPP CEP55 CEP85L CFAP53 CLK1 CNOT7 COL20A1 CXCL14 DMTN DUSP21 DUSP6 EFHC1 EXOSC1 EXOSC5 FAAP20 FAM156A FAM161B FAM217A FBF1 GATAD2B GPSM3 GRXCR1 HOXB5 HYI ING3 KANK2 KCTD10 KIAA0408 KIAA1217 KRT6B LIN37 LRCH2 LRRC36 LSM2 MAD1L1 MAPK9 MAPKBP1 MORF4L1 MRFAP1 MRFAP1L1 MTA1 MYEF2 NECAB2 NEFL NRIP1 PDZD11 PEX39 PIAS1 POM121 PPP1R18 PRPSAP2 PTPDC1 QKI REXO1L6P RIBC1 RIBC2 SCAF8 SEPTIN1 SH3GLB2 SHOC1 SNW1 SNX32 SNX6 SNX7 SOX5 SPMIP5 STMN2 SUPT5H TBC1D22B TCHP TIPIN TOPBP1 TSC22D4 TSG101 USP15 UTP14C VIL1 ZNF414
Entrez ID		2039	56159
HPRD ID		00506	02256
Ensembl ID		ENSG00000158856	ENSG00000120498
Uniprot IDs		Q08495	Q8IYF3
PDB IDs		1QZP 1ZV6
Enriched GO Terms of Interacting Partners?		Regulation Of Norepinephrine Uptake Transporter Regulator Activity Regulation Of Endocytosis Positive Regulation Of Endocytosis Cytoskeleton Protein-containing Complex Cell Junction Organization Postsynapse Cellular Response To Epinephrine Stimulus Positive Regulation Of Transport Cellular Component Assembly Protein Tetramerization Regulation Of Monoatomic Cation Transmembrane Transport Synapse Organization Response To Epinephrine Structural Constituent Of Cytoskeleton Actin Cytoskeleton Regulation Of Vesicle-mediated Transport Regulation Of Monoatomic Ion Transmembrane Transport Regulation Of Neurotransmitter Uptake Cytoplasm Cytoskeleton Organization Cellular Response To Copper Ion Regulation Of Presynapse Organization Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Presynapse Assembly Regulation Of Metal Ion Transport Regulation Of Generation Of Precursor Metabolites And Energy Cortical Cytoskeleton Regulation Of Synaptic Vesicle Recycling Regulation Of Calcium Ion Transmembrane Transport Perinuclear Region Of Cytoplasm Regulation Of Protein Catabolic Process Amyloid Fibril Formation Microglial Cell Activation Negative Regulation Of Catabolic Process Cell Maturation Positive Regulation Of Small Molecule Metabolic Process Leukocyte Activation Involved In Inflammatory Response Response To Copper Ion Regulation Of Monoatomic Ion Transport Inorganic Ion Homeostasis Cell Cortex Regulation Of Cellular Component Organization Kinesin Binding Protein Kinase Binding Tau Protein Binding Positive Regulation Of Norepinephrine Uptake Cellular Response To Cytochalasin B Amyloid-beta Complex	Axonemal A Tubule Inner Sheath Protein Binding Cytoskeleton Sperm Motility Flagellated Sperm Motility Cilium-dependent Cell Motility RNA Exonuclease Activity Cilium Movement Involved In Cell Motility Cyclin D2-CDK4 Complex Negative Regulation Of Peptidyl-tyrosine Phosphorylation Motile Cilium Spindle Pole
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