DRC5 and KLHDC3

		DRC5	KLHDC3
Description		dynein regulatory complex subunit 5	kelch domain containing 3
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GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Cilium Motile Cilium Sperm Flagellum Cell Projection	Chromatin Nucleoplasm Cytoplasm Cytosol Cul2-RING Ubiquitin Ligase Complex
	Molecular Function	Protein Binding	Chromatin Binding Protein Binding Ubiquitin-like Ligase-substrate Adaptor Activity
	Biological Process	Microtubule-based Movement Flagellated Sperm Motility	Reciprocal Meiotic Recombination Protein Ubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Meiotic Cell Cycle Ubiquitin-dependent Protein Catabolic Process Via The C-end Degron Rule Pathway
Pathways			XBP1(S) activates chaperone genes
Drugs
Diseases
GWAS
Interacting Genes		7 interacting genes: KLC4 KLHDC3 LINC03040 LRRC73 RSPH9 SPATS1 TAF8	5 interacting genes: DRC5 ENAH HLA-DQA1 RSPH9 UBC
Entrez ID		202500	116138
HPRD ID		14568	13922
Ensembl ID		ENSG00000146221	ENSG00000124702
Uniprot IDs		Q5JU00	Q9BQ90
PDB IDs		8J07	9D1I 9D1Y 9D1Z
Enriched GO Terms of Interacting Partners?		DNA-templated Transcription Open Complex Formation Radial Spoke Head 1 Radial Spoke Assembly Radial Spoke Head 3 Axonemal Central Apparatus Assembly Radial Spoke Head	Endocytic Vesicle Membrane Sperm Flagellum Cilium Movement Cilium Movement Involved In Cell Motility Radial Spoke Head 1 Radial Spoke Assembly Radial Spoke Head 3 Motile Cilium Axonemal Central Apparatus Assembly Radial Spoke Head Actin Polymerization-dependent Cell Motility Endosome Membrane MHC Class II Receptor Activity Kinocilium Profilin Binding Cell Projection Radial Spoke Peptide Antigen Assembly With MHC Class II Protein Complex Protein Tag Activity MHC Class II Protein Complex Microtubule-based Movement Cytoskeleton Postsynaptic Cytoskeleton Organization WW Domain Binding MHC Class II Protein Complex Binding Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Lumenal Side Of Endoplasmic Reticulum Membrane Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II 9+2 Motile Cilium Peptide Antigen Binding Cilium
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