TXLNB and NMI

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid, two hybrid)

		TXLNB	NMI
Description		taxilin beta	N-myc and STAT interactor
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Extracellular Region Extracellular Space Nucleus Nucleoplasm Cytoplasm Cytosol Membrane
	Molecular Function	Protein Binding Syntaxin Binding	Protein Binding Identical Protein Binding
	Biological Process		Macrophage Activation Involved In Immune Response Immune System Process Cell Surface Receptor Signaling Pathway Via JAK-STAT Negative Regulation Of Cell Population Proliferation Response To Virus Negative Regulation Of Type I Interferon Production Negative Regulation Of Interferon-alpha Production Negative Regulation Of Interferon-beta Production Toll-like Receptor 4 Signaling Pathway Innate Immune Response Regulation Of Innate Immune Response Positive Regulation Of Innate Immune Response Negative Regulation Of Innate Immune Response Positive Regulation Of Inflammatory Response Protein K48-linked Ubiquitination Negative Regulation Of Non-canonical NF-kappaB Signal Transduction Positive Regulation Of Non-canonical NF-kappaB Signal Transduction Positive Regulation Of Protein K48-linked Ubiquitination
Pathways			SARS-CoV-1 activates/modulates innate immune responses
Drugs
Diseases
GWAS		Albumin-globulin ratio ( 29403010) Caudate volume in trauma-exposed individuals ( 29187748) Heel bone mineral density ( 30598549) Non-albumin protein levels ( 29403010) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		67 interacting genes: AXIN2 BTF3 BTF3L4 C18orf54 CAGE1 CBY2 CCDC13 CCDC14 CCDC152 CCDC196 CCDC88B CCHCR1 CDR2 CEP19 CEP57 CEP57L1 CEP70 CFAP53 CT55 DCTN2 DEUP1 DMAP1 DRC4 DYDC1 EXOC5 FAM161A FAM167A GOLGA2 HAUS3 KIAA1328 KRT13 KRT15 KRT16 KRT26 KRT27 KRT34 KRT35 KRT37 KRT38 KRT39 KRT6A KRT75 LPXN LZTS1 MBIP MEOX2 MNS1 NEFL NF2 NMI ODAD3 SIKE1 SNAPC5 SOX13 STMN3 STX1A STX4 TADA3 TCL1A TXLNA UBE2I USHBP1 UTP14A VIM VPS52 WASHC3 ZNF20	59 interacting genes: ANKRD13C-DT BRAT1 BRCA1 BRMS1 C1orf216 CDKN2A CDKN2D CNKSR3 CNOT7 COPS7B CYP2E1 EMILIN1 EPC2 EXOSC5 GART GCSH GOLGA8EP HDDC3 HGS HOXC9 HSPA8 HSPH1 IFI35 KDM1A LCA5L LSM4 MAD2L1BP MCPH1 MORF4L1 MTMR6 MTMR9 MYC MYCN MYOM3 NECAP2 POMZP3 PSMA1 RYBP SCEL SFR1 SH3GLB2 SINHCAF SNAPC5 SOX10 STAT1 STAT3 STAT4 STAT5A STAT5B STAT6 THAP8 TRAF5 TRIM72 TRIP12 TUBA3C TUBA3E TXLNA TXLNB UBE2I
Entrez ID		167838	9111
HPRD ID		10793	04632
Ensembl ID		ENSG00000164440	ENSG00000123609
Uniprot IDs		Q8N3L3	Q13287
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Structural Constituent Of Skin Epidermis Intermediate Filament Keratin Filament Cytoskeleton Cytoskeleton Organization Supramolecular Fiber Organization Organelle Organization Structural Molecule Activity Epithelial Cell Differentiation Morphogenesis Of An Epithelium Cytosol Tissue Morphogenesis Protein Binding Microtubule Cytoskeleton Organization Microtubule-based Process Cell Projection Cilium Organization Anatomical Structure Morphogenesis Centrosome Centriole Structural Constituent Of Cytoskeleton Cilium Sperm Flagellum Mitotic Spindle Ciliary Basal Body Gamma-tubulin Binding Polymeric Cytoskeletal Fiber Identical Protein Binding Microtubule Binding Cell Differentiation Plasma Membrane Bounded Cell Projection Organization Microtubule Organizing Center Cilium Assembly Schaffer Collateral - CA1 Synapse Epithelial Cilium Movement Involved In Extracellular Fluid Movement Osteoblast Proliferation Extracellular Transport Syntaxin Binding Intermediate Filament Cytoskeleton Cell Projection Organization SNARE Complex Assembly Flagellated Sperm Motility Negative Regulation Of Osteoblast Proliferation Epithelial Cilium Movement Involved In Determination Of Left/right Asymmetry Sperm Motility Exocytosis Axoneme	Nucleoplasm Cell Surface Receptor Signaling Pathway Via JAK-STAT Growth Hormone Receptor Signaling Pathway Via JAK-STAT Cell Surface Receptor Signaling Pathway Via STAT Growth Hormone Receptor Signaling Pathway Interleukin-9-mediated Signaling Pathway Negative Regulation Of Signal Transduction Negative Regulation Of Cell Communication Negative Regulation Of Signaling Regulation Of Cell Population Proliferation RNA Polymerase II Transcription Regulator Complex Negative Regulation Of RNA Metabolic Process Negative Regulation Of Developmental Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Nucleic Acid Metabolic Process Regulation Of Programmed Cell Death Regulation Of Erythrocyte Differentiation Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Cell Population Proliferation Development Of Secondary Female Sexual Characteristics Development Of Secondary Male Sexual Characteristics DNA-binding Transcription Factor Binding Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Sin3-type Complex Regulation Of Apoptotic Process Nucleobase-containing Compound Metabolic Process Negative Regulation Of Metabolic Process Negative Regulation Of Macromolecule Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process DNA-binding Transcription Factor Activity Positive Regulation Of RNA Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Cell Differentiation DNA-templated Transcription Positive Regulation Of Mesenchymal Cell Proliferation Regulation Of Macromolecule Metabolic Process Positive Regulation Of Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Mitotic Cell Cycle Negative Regulation Of Biosynthetic Process Positive Regulation Of Macromolecule Metabolic Process Development Of Secondary Sexual Characteristics Positive Regulation Of Gene Expression Regulation Of Myeloid Cell Apoptotic Process Positive Regulation Of Metabolic Process
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