TTC23L and CBY1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		TTC23L	CBY1
Description		tetratricopeptide repeat domain 23 like	chibby 1, beta catenin antagonist
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centrosome Spindle Cytoskeleton Midbody	Nucleus Nucleoplasm Nucleolus Cytoplasm Golgi Apparatus Trans-Golgi Network Centrosome Centriole Cytosol Cytoskeleton Cilium Nuclear Speck Motile Cilium Ciliary Basal Body Sperm Flagellum Cell Projection
	Molecular Function	Protein Binding	Protein Binding Beta-catenin Binding Identical Protein Binding Protein Homodimerization Activity
	Biological Process	Response To Endoplasmic Reticulum Stress	Intracellular Protein Localization Cell Projection Organization Cell Differentiation Negative Regulation Of Wnt Signaling Pathway Floor Plate Development Fat Cell Differentiation Negative Regulation Of DNA-templated Transcription Protein Homotetramerization Cardiac Muscle Cell Differentiation Canonical Wnt Signaling Pathway Cilium Assembly Negative Regulation Of Canonical Wnt Signaling Pathway
Pathways			Deactivation of the beta-catenin transactivating complex
Drugs
Diseases
GWAS		Daytime sleep phenotypes ( 27126917) Dysphagia ( 26116289)	Resting heart rate ( 27798624) Sleep duration ( 30846698)
Interacting Genes		21 interacting genes: AIRIM ANKRD11 CALCOCO2 CBY1 CCDC24 DNAAF11 DPF2 EFHC1 EGLN3 EXOC5 FAM161B MIA2 MSGN1 PICK1 SCNM1 SPG21 TSGA10IP UBE3A USP20 VPS9D1 ZNF784	18 interacting genes: AGTPBP1 CDK6 CFAP53 CIBAR1 CLU CTNNB1 DDIAS DZIP1L ENKD1 FAM161B GORASP2 LNX1 NBPF11 RALBP1 RASSF10 TNFAIP8L3 TSG101 TTC23L
Entrez ID		153657	25776
HPRD ID		08691	09676
Ensembl ID		ENSG00000205838	ENSG00000100211
Uniprot IDs		A0A3B3IS63 Q6PF05	Q9Y3M2
PDB IDs			4WRQ
Enriched GO Terms of Interacting Partners?		Cilium Organization	Cytoskeleton Spindle Pole Ciliary Basal Body Cilium Cilium Organization Centriole Cytoplasm Centrosome Organelle Assembly Microtubule Cytoskeleton Cilium Assembly Establishment Of Organelle Localization Negative Regulation Of Intrinsic Apoptotic Signaling Pathway Organelle Organization Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Plasma Membrane Bounded Cell Projection Assembly Cell Projection Assembly Ciliary Transition Zone Cell Projection Cyclin D3-CDK6 Complex T Cell Differentiation In Thymus Cyclin D1-CDK6 Complex Cyclin D2-CDK6 Complex Negative Regulation Of Myeloid Leukocyte Differentiation FBXO Family Protein Binding Establishment Of Protein Localization To Vacuole Perinuclear Endoplasmic Reticulum Lumen Positive Regulation Of Neurofibrillary Tangle Assembly Negative Regulation Of Apoptotic Signaling Pathway Regulation Of Intrinsic Apoptotic Signaling Pathway Regulation Of Neuronal Signal Transduction Cellular Component Assembly Mesenchymal Stem Cell Differentiation Positive Regulation Of Determination Of Dorsal Identity Negative Regulation Of Mitotic Cell Cycle, Embryonic Beta-catenin-ICAT Complex Positive Regulation Of Neural Precursor Cell Proliferation Negative Regulation Of Mesenchymal To Epithelial Transition Involved In Metanephros Morphogenesis Glial Cell Fate Determination Renal Inner Medulla Development Scrib-APC-beta-catenin Complex Organelle Localization Renal Outer Medulla Development Renal Vesicle Formation Canonical Wnt Signaling Pathway Involved In Mesenchymal Stem Cell Differentiation Positive Regulation Of Branching Involved In Lung Morphogenesis Neural Plate Development Extracellular Transport Positive Regulation Of Ubiquitin-dependent Endocytosis Doxorubicin Transport
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