SMYD1 and CFAP263

Number of citations of the paper that reports this interaction (PubMedID 23455924)
0

Data Source:
BioGRID (two hybrid)

		SMYD1	CFAP263
Description		SET and MYND domain containing 1	cilia and flagella associated protein 263
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Cytoplasm Cytoskeleton Cilium Axoneme Protein-containing Complex Centriolar Satellite Ciliary Basal Body Cell Projection
	Molecular Function	DNA Binding Transcription Corepressor Activity Protein Binding Methyltransferase Activity Zinc Ion Binding Transferase Activity Histone H3K4 Methyltransferase Activity Metal Ion Binding Histone H3K4 Trimethyltransferase Activity	Protein Binding
	Biological Process	Chromatin Remodeling Heart Development Positive Regulation Of Myotube Differentiation Methylation Skeletal Muscle Cell Differentiation Positive Regulation Of Myoblast Differentiation Negative Regulation Of DNA-templated Transcription	Cell Projection Organization Cilium Assembly
Pathways		Cardiogenesis
Drugs
Diseases
GWAS		Night sleep phenotypes ( 27126917) Retinal detachment or retinal break ( 31816047)
Interacting Genes		45 interacting genes: ARID5A BACH2 BHLHE40 C11orf16 CCDC33 CFAP263 CFAP68 CFTR CIMIP2A DISC1 DVL1 FAM204A FAM83A FAM86C1P H3-5 HDAC2 HDAC3 HDHD3 HMG20A HOMEZ KIF16B KRT35 LENG8 MDFI MEOX2 MYH7B NACA NEFL OGDHL PATZ1 POU2AF2 POU6F2 PRR22 RBM4B RSPH6A RUSC1 SNX11 SPAG8 TBRG1 TTC33 USP54 UTP14A WDR77 ZBTB3 ZBTB44	6 interacting genes: GIT1 HAP1 HSF2BP IMMT PFN2 SMYD1
Entrez ID		150572	29070
HPRD ID		06025	07121
Ensembl ID		ENSG00000115593	ENSG00000103021
Uniprot IDs		E9PHG3 Q8NB12	Q9H0I3
PDB IDs			8J07
Enriched GO Terms of Interacting Partners?		Circadian Regulation Of Gene Expression Protein Decrotonylase Activity Histone Decrotonylase Activity Protein De-2-hydroxyisobutyrylase Activity Protein Lysine Delactylase Activity Axonemal A Tubule Inner Sheath Microtubule-based Process Regulation Of Transcription By RNA Polymerase II Deacetylase Activity Histone Deacetylase Activity, Hydrolytic Mechanism Sperm Flagellum Cilium Movement Involved In Cell Motility Circadian Rhythm Protein Lysine Deacetylase Activity Microtubule-based Movement	Regulation Of Exocytosis Presynapse Presynaptic Modulation Of Chemical Synaptic Transmission Regulation Of Synaptic Vesicle Exocytosis Positive Regulation Of Protein Polymerization Positive Regulation Of Cellular Component Biogenesis Regulation Of Neurotransmitter Secretion Regulation Of Secretion By Cell Positive Regulation Of Organelle Organization Regulation Of Vesicle-mediated Transport Modulation Of Chemical Synaptic Transmission Positive Regulation Of Neurotrophin Production Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Negative Regulation Of ARF Protein Signal Transduction Structural Constituent Of Postsynaptic Specialization Regulation Of Secretion Regulation Of Regulated Secretory Pathway Brain-derived Neurotrophic Factor Binding Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Growth Cone Positive Regulation Of Supramolecular Fiber Organization Presynaptic Actin Cytoskeleton Organization Positive Regulation Of Protein-containing Complex Assembly Positive Regulation Of Cytoskeleton Organization Hypothalamus Cell Differentiation Mitochondrial Crista Junction Intramembranous Ossification Presynaptic Cytoskeleton Organization Negative Regulation Of Ruffle Assembly MICOS Complex Female Meiosis I Motor Learning Regulation Of Cell Projection Assembly Postsynapse Brain Development Synapse Organization Regulation Of Microtubule-based Process Regulation Of Organelle Transport Along Microtubule Positive Regulation Of Non-motile Cilium Assembly SAM Complex MIB Complex Double-strand Break Repair Involved In Meiotic Recombination Positive Regulation Of Receptor Catabolic Process Positive Regulation Of Microtubule Nucleation Maintenance Of Postsynaptic Specialization Structure Negative Regulation Of Inflammatory Response To Wounding Histone H3K4 Trimethyltransferase Activity Modification Of Postsynaptic Actin Cytoskeleton Regulation Of Non-motile Cilium Assembly Cristae Formation
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