MOB3C and CMTM3

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		MOB3C	CMTM3
Description		MOB kinase activator 3C	CKLF like MARVEL transmembrane domain containing 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Extracellular Space Cytoplasm Cytosol Membrane Cytoplasmic Vesicle Nuclear Membrane
	Molecular Function	Protein Binding Protein Kinase Activator Activity Metal Ion Binding	Cytokine Activity Protein Binding
	Biological Process	Signal Transduction	Blastocyst Hatching Chemotaxis Signal Transduction Positive Regulation Of B Cell Receptor Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Chronic kidney disease ( 30226566) Hypertension ( 30226566)
Interacting Genes		18 interacting genes: APP CMTM3 FAM118A FBXO7 IKZF4 KANK2 KRT40 LATS1 LATS2 NT5C2 PCYT1A PICK1 PTPN21 SIAH1 TDO2 TFCP2 TNIP1 ZBTB10	32 interacting genes: APOA5 APP AQP6 ARL13B BLNK BTK CREB3L1 DHX38 ELOVL4 GJB1 GPR35 HSD17B11 IKBIP IL10RA LEUTX LMNA LRRC59 MAPK1 MEST MOB1A MOB3C MRM1 NDRG4 RABAC1 REEP4 RETREG3 SLC10A1 SLC71A2 SPP1 STMN4 SYT2 VEZT
Entrez ID		148932	123920
HPRD ID		17584	16259
Ensembl ID		ENSG00000142961	ENSG00000140931
Uniprot IDs		Q70IA8 X6R3L3	H3BUD5 J3KSR6 Q96MX0
PDB IDs
Enriched GO Terms of Interacting Partners?		Inner Cell Mass Cell Fate Commitment Inner Cell Mass Cellular Morphogenesis Negative Regulation Of Protein Localization To Nucleus Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Negative Regulation Of Cyclin-dependent Protein Kinase Activity Amide Catabolic Process Negative Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Signaling Amyloid Fibril Formation Regulation Of Protein Localization To Nucleus Cytosol Positive Regulation Of Receptor Internalization Negative Regulation Of Cell Communication Identical Protein Binding Phosphate-containing Compound Metabolic Process Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Hippo Signaling Negative Regulation Of Cell Cycle Negative Regulation Of Protein Serine/threonine Kinase Activity Positive Regulation Of NLRP3 Inflammasome Complex Assembly Positive Regulation Of Hippo Signaling Amyloid-beta Complex Protein Homooligomerization Growth Cone Lamellipodium Neuron Projection Organization Negative Regulation Of Wnt Signaling Pathway Regulation Of Response To Calcium Ion Amylin Binding Regulation Of Intrinsic Apoptotic Signaling Pathway Regulation Of Supramolecular Fiber Organization Positive Regulation Of Toll Signaling Pathway Protein Modification Process L-tryptophan Catabolic Process To Acetyl-CoA Regulation Of Hippo Signaling Regulation Of Intracellular Estrogen Receptor Signaling Pathway Nucleoside Phosphotransferase Activity GMP Catabolic Process To Guanine Glial Cytoplasmic Inclusion Classical Lewy Body Lewy Body Corona Lewy Neurite Regulation Of NLRP3 Inflammasome Complex Assembly Protein Metabolic Process Negative Regulation Of Protein Localization Positive Regulation Of Receptor-mediated Endocytosis Acetylcholine Receptor Activator Activity Positive Regulation Of Apoptotic Process Lipoprotein Particle Positive Regulation Of Protein Import Glial Cell Development
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