CMTM3 and SYT2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CMTM3	SYT2
Description		CKLF like MARVEL transmembrane domain containing 3	synaptotagmin 2
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Cytoplasm Cytosol Membrane Cytoplasmic Vesicle Nuclear Membrane	Cytoplasm Plasma Membrane Membrane Axon Clathrin-coated Endocytic Vesicle Membrane Synaptic Vesicle Membrane Dense Core Granule Cytoplasmic Vesicle Chromaffin Granule Membrane Synapse Exocytic Vesicle
	Molecular Function	Cytokine Activity Protein Binding	SNARE Binding Protein Binding Calcium-dependent Phospholipid Binding Inositol 1,3,4,5 Tetrakisphosphate Binding Metal Ion Binding Calcium Ion Sensor Activity
	Biological Process	Blastocyst Hatching Chemotaxis Signal Transduction Positive Regulation Of B Cell Receptor Signaling Pathway	Vesicle-mediated Transport Regulation Of Calcium Ion-dependent Exocytosis Cell Differentiation Calcium-dependent Activation Of Synaptic Vesicle Fusion Positive Regulation Of Dendrite Extension Regulation Of Synaptic Vesicle Exocytosis
Pathways			Toxicity of botulinum toxin type B (botB) Neurexins and neuroligins Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
Drugs			Botulinum toxin type B
Diseases
GWAS			Celiac disease ( 23936387) Epilepsy and lamotrigine-induced maculopapular eruptions ( 26220383)
Interacting Genes		32 interacting genes: APOA5 APP AQP6 ARL13B BLNK BTK CREB3L1 DHX38 ELOVL4 GJB1 GPR35 HSD17B11 IKBIP IL10RA LEUTX LMNA LRRC59 MAPK1 MEST MOB1A MOB3C MRM1 NDRG4 RABAC1 REEP4 RETREG3 SLC10A1 SLC71A2 SPP1 STMN4 SYT2 VEZT	29 interacting genes: AQP10 BNIP2 CCDC167 CLDN4 CMTM3 FA2H FUNDC2 ITGAM KLHL3 LAT MALL MIP NAPB NRXN1 ORMDL3 PLPP4 PMP22 SLC30A8 SLC35A1 SLC35A4 STON2 SYNCRIP TF THSD7B TMEM107 TMEM229B TSPO2 VAMP4 WNK1
Entrez ID		123920	127833
HPRD ID		16259	02520
Ensembl ID		ENSG00000140931	ENSG00000143858
Uniprot IDs		H3BUD5 J3KSR6 Q96MX0	Q8N9I0
PDB IDs			6G5G
Enriched GO Terms of Interacting Partners?			Membrane Pyrimidine Nucleotide-sugar Transmembrane Transporter Activity Transmembrane Transport Pyrimidine Nucleotide-sugar Transmembrane Transport Nucleotide-sugar Transmembrane Transport Homeostatic Process Endocytic Vesicle Water Channel Activity Chemical Homeostasis
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