SPMIP4 and TEKT5

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SPMIP4	TEKT5
Description		sperm microtubule inner protein 4	tektin 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centrosome Cytoskeleton Cilium Motile Cilium Cell Projection	Nucleus Cytoplasm Cytoskeleton Cilium Microtubule Cytoskeleton Motile Cilium Sperm Flagellum Cell Projection Axonemal A Tubule Inner Sheath
	Molecular Function	Protein Binding	Protein Binding
	Biological Process		Flagellated Sperm Motility Cilium Assembly Cilium Movement Involved In Cell Motility
Pathways
Drugs
Diseases
GWAS			Cerebrospinal AB1-42 levels in normal cognition ( 29274321) Chronic obstructive pulmonary disease ( 30804561) Eating disorders ( 23568457) Lung adenocarcinoma ( 28604730) Lung function (FEV1/FVC) ( 26635082 30804560) Neonatal total 25-hydroxyvitamin D levels (maternal genetic effect) ( 32047095) Nickel levels ( 26025379) Normal facial asymmetry (angle of surface orientation score) ( 30631343) Peak expiratory flow ( 30804560) Resting heart rate ( 27798624)
Interacting Genes		11 interacting genes: APP BCL6 CLCNKA CLIC3 CYSRT1 HSF2BP KCTD9 KLHL40 OIP5 PFDN5 TEKT5	47 interacting genes: ACTMAP AKAP8L BAG4 CABP2 CSKMT DTX2 EPHB6 EYA2 FNDC3B FOXH1 FOXI1 GSK3B HGS HOXA1 HOXB6 KLHL38 KRTAP12-4 KRTAP15-1 KRTAP19-6 KRTAP19-7 KRTAP6-2 LASP1 MAPKBP1 MGAT5B NFKBID NHLRC2 PITX1 PLSCR4 PROP1 PSMB4 QRICH1 RBPMS RORB RUNX1 SMARCB1 SMUG1 SPAG8 SPMIP4 SSC4D TBX15 TLX3 TNS2 TOX2 USP54 VENTX ZMYND12 ZNF76
Entrez ID		136895	146279
HPRD ID		12919	08736
Ensembl ID		ENSG00000153790	ENSG00000153060
Uniprot IDs		Q8N865	Q96M29
PDB IDs
Enriched GO Terms of Interacting Partners?		Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Myeloid Cell Development Regulation Of Protein Import Epigenetic Regulation Of Gene Expression Regulation Of Response To Calcium Ion Regulation Of Amyloid Fibril Formation Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Positive Regulation Of Neuron Differentiation Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Identical Protein Binding Negative Regulation Of Isotype Switching To IgE Isotypes Regulation Of Mitotic Cell Cycle DNA Replication Negative Regulation Of Mitotic Cell Cycle DNA Replication Negative Regulation Of Mast Cell Cytokine Production Isotype Switching To IgE Isotypes Negative Regulation Of Plasma Cell Differentiation Intronic Transcription Regulatory Region Sequence-specific DNA Binding Chloride Channel Complex Chloride Transmembrane Transport Chloride Channel Activity RNA Polymerase III Assembly RNA Polymerase I Assembly RNA Polymerase II Core Complex Assembly Protein-disulfide Reductase (glutathione) Activity Pericentric Heterochromatin Organization CENP-A Recruiting Complex	Positive Regulation Of RNA Biosynthetic Process Sequence-specific Double-stranded DNA Binding Positive Regulation Of DNA-templated Transcription Positive Regulation Of Nucleobase-containing Compound Metabolic Process DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Positive Regulation Of RNA Metabolic Process Chromatin Positive Regulation Of Transcription By RNA Polymerase II DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Positive Regulation Of Macromolecule Biosynthetic Process Intermediate Filament Positive Regulation Of Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Protein Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Positive Regulation Of Macromolecule Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Metabolic Process Regulation Of RNA Biosynthetic Process Regulation Of Nucleobase-containing Compound Metabolic Process Hepatocyte Differentiation
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