ERICH6 and IGSF10

		ERICH6	IGSF10
Description		glutamate rich 6	immunoglobulin superfamily member 10
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Extracellular Region
	Molecular Function
	Biological Process		Ossification Cell Differentiation Regulation Of Neuron Migration
Pathways
Drugs			Pyridoxal phosphate
Diseases
GWAS			Refractive error ( 32231278)
Interacting Genes		3 interacting genes: CDC42 HSPB1 IGSF10	5 interacting genes: AADACL2 APP EIF2A ERICH6 MED12L
Entrez ID		131831	285313
HPRD ID		17543	13732
Ensembl ID		ENSG00000163645	ENSG00000152580
Uniprot IDs		Q7L0X2	Q6WRI0
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Cell Motility Regulation Of Cell Migration Regulation Of Locomotion Endothelin Receptor Signaling Pathway Involved In Heart Process Microtubule-based Transport Transport Along Microtubule GBD Domain Binding Spindle Storage Vacuole Cytoskeleton-dependent Intracellular Transport Negative Regulation Of Protein Kinase C Signaling Protein Kinase C Inhibitor Activity Apolipoprotein A-I Receptor Binding Neuropilin Signaling Pathway Regulation Of Protein Kinase C Signaling Leading Edge Membrane Positive Regulation Of Pseudopodium Assembly Endothelin Receptor Signaling Pathway Thioesterase Binding Positive Regulation Of Pinocytosis Protein Kinase Binding Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis G Protein-coupled Receptor Signaling Pathway Involved In Heart Process Focal Adhesion Neuron Fate Determination Cardiac Neural Crest Cell Migration Involved In Outflow Tract Morphogenesis Establishment Of Golgi Localization Golgi Transport Complex Microtubule-based Movement Positive Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis Protein Transport Along Microtubule Anterograde Axonal Protein Transport Contractile Muscle Fiber Golgi Localization Positive Regulation Of Endothelial Cell Chemotaxis Cardiac Conduction System Development Establishment Of Epithelial Cell Apical/basal Polarity Cell Migration Involved In Heart Development Positive Regulation Of Cell Migration Dendritic Spine Morphogenesis Regulation Of Attachment Of Spindle Microtubules To Kinetochore Establishment Of Apical/basal Cell Polarity Positive Regulation Of Locomotion Dendritic Cell Migration Establishment Of Monopolar Cell Polarity GTP-dependent Protein Binding Heart Contraction Embryonic Heart Tube Development Positive Regulation Of Cell Motility Filopodium Assembly	Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Regulation Of Response To Calcium Ion Axon Midline Choice Point Recognition Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Amyloid Fibril Formation Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Lipoprotein Particle Growth Factor Receptor Binding Main Axon Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Astrocyte Activation Involved In Immune Response Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Low-density Lipoprotein Particle Mediated Signaling Eukaryotic Translation Initiation Factor 2 Complex Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Axon Choice Point Recognition Heparan Sulfate Binding Signaling Receptor Activator Activity Peptidase Activator Activity Cellular Response To Manganese Ion Cellular Response To Sterol Depletion SREBP Signaling Pathway Negative Regulation Of Blood Circulation Regulation Of Superoxide Anion Generation Collateral Sprouting Heparan Sulfate Proteoglycan Binding Regulation Of Translation Acetylcholine Receptor Binding Golgi-associated Vesicle Insulin Receptor Binding Apolipoprotein Binding Response To Lead Ion Regulation Of Calcium Ion Transmembrane Transport Via High Voltage-gated Calcium Channel
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