IGSF10 and AADACL2

		IGSF10	AADACL2
Description		immunoglobulin superfamily member 10	arylacetamide deacetylase like 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region	Extracellular Region Membrane
	Molecular Function		Catalytic Activity Hydrolase Activity Carboxylic Ester Hydrolase Activity
	Biological Process	Ossification Cell Differentiation Regulation Of Neuron Migration
Pathways
Drugs		Pyridoxal phosphate	Gibberellic acid Gibberellin A4
Diseases
GWAS		Refractive error ( 32231278)	Breast cancer and/or colorectal cancer ( 29698419) Male-pattern baldness ( 28196072)
Interacting Genes		5 interacting genes: AADACL2 APP EIF2A ERICH6 MED12L	1 interacting genes: IGSF10
Entrez ID		285313	344752
HPRD ID		13732	14705
Ensembl ID		ENSG00000152580	ENSG00000197953
Uniprot IDs		Q6WRI0	Q6P093
PDB IDs
Enriched GO Terms of Interacting Partners?		Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Regulation Of Response To Calcium Ion Axon Midline Choice Point Recognition Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Amyloid Fibril Formation Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Lipoprotein Particle Growth Factor Receptor Binding Main Axon Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Astrocyte Activation Involved In Immune Response Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Low-density Lipoprotein Particle Mediated Signaling Eukaryotic Translation Initiation Factor 2 Complex Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Axon Choice Point Recognition Heparan Sulfate Binding Signaling Receptor Activator Activity Peptidase Activator Activity Cellular Response To Manganese Ion Cellular Response To Sterol Depletion SREBP Signaling Pathway Negative Regulation Of Blood Circulation Regulation Of Superoxide Anion Generation Collateral Sprouting Heparan Sulfate Proteoglycan Binding Regulation Of Translation Acetylcholine Receptor Binding Golgi-associated Vesicle Insulin Receptor Binding Apolipoprotein Binding Response To Lead Ion Regulation Of Calcium Ion Transmembrane Transport Via High Voltage-gated Calcium Channel	Regulation Of Neuron Migration
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