COPB1 and ANO1

Number of citations of the paper that reports this interaction (PubMedID 27207835)
0

Data Source:
BioGRID (two hybrid)

		COPB1	ANO1
Description		coat protein complex I subunit beta 1	anoctamin 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Golgi-associated Vesicle Cytosol Plasma Membrane Membrane Membrane Coat COPI Vesicle Coat Transport Vesicle COPI-coated Vesicle COPI-coated Vesicle Membrane Secretory Granule Membrane Cytoplasmic Vesicle Tertiary Granule Membrane Ficolin-1-rich Granule Membrane	Nucleoplasm Plasma Membrane Membrane Apical Plasma Membrane Chloride Channel Complex Cell Projection Synapse Extracellular Exosome Presynapse
	Molecular Function	Structural Molecule Activity Protein Binding	Signaling Receptor Binding Calcium-activated Cation Channel Activity Intracellularly Calcium-gated Chloride Channel Activity Voltage-gated Chloride Channel Activity Chloride Channel Activity Protein Binding Iodide Transmembrane Transporter Activity Identical Protein Binding Protein Homodimerization Activity Metal Ion Binding Protein Dimerization Activity
	Biological Process	Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Intra-Golgi Vesicle-mediated Transport Protein Transport Vesicle-mediated Transport	Monoatomic Ion Transport Chloride Transport Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Iodide Transport Monoatomic Ion Transmembrane Transport Cellular Response To Heat Detection Of Temperature Stimulus Involved In Sensory Perception Of Pain Mucus Secretion Protein Localization To Membrane Monoatomic Cation Transmembrane Transport Glial Cell Projection Elongation Cellular Response To Peptide Chloride Transmembrane Transport
Pathways		Neutrophil degranulation COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic	Stimuli-sensing channels Induction of Cell-Cell Fusion
Drugs			Crofelemer
Diseases
GWAS		HDL cholesterol ( 26780889) HDL cholesterol levels ( 28334899 32203549) Height ( 31562340) High chromosomal aberration frequency (total) ( 31586183) Hip circumference adjusted for BMI ( 34021172) Vitamin D levels ( 25208829)	A body shape index ( 34021172) Appendicular lean mass ( 33097823) Basophil count ( 32888494) Birth weight ( 31043758) Childhood ear infection ( 27182965 28928442) Diastolic blood pressure ( 30224653) Eosinophil count ( 32888494) Eosinophil percentage of white cells ( 32888494) Haemorrhoidal disease ( 33888516) Monobrow ( 27182965) Survival in rectal cancer ( 25866641) Systolic blood pressure ( 30578418) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		46 interacting genes: ADAM19 ANO1 APP ARCN1 ARF1 BCAR1 COPE COPG1 COPG2 DSCR9 ERBIN FOXB1 GORAB GRB2 GTPBP4 HLA-DPB1 HLA-G ID1 IRAK3 KCNK3 KDELR1 KIAA1328 LINC00839 LZTS1 LZTS2 NUB1 PDGFRB PRKCE PTEN RGS2 RGS4 RHOQ RNF10 SERTAD1 SNTA1 SPTBN1 TANK TAPBP TMED10 TRIM37 TTYH2 UBC UBQLN4 VPS18 WBP2 XRCC6	3 interacting genes: COPB1 SHANK2 TRIM23
Entrez ID		1315	55107
HPRD ID		02981	18202
Ensembl ID		ENSG00000129083	ENSG00000131620
Uniprot IDs		P53618	Q5XXA6 Q9NW72
PDB IDs
Enriched GO Terms of Interacting Partners?		COPI-coated Vesicle Membrane Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum COPI Vesicle Coat COPI-coated Vesicle Transport Vesicle Golgi Vesicle Transport Vesicle-mediated Transport Golgi Membrane Negative Regulation Of Glycine Import Across Plasma Membrane Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Establishment Of Protein Localization Positive Regulation Of Reactive Oxygen Species Metabolic Process Golgi Apparatus Regulation Of Actin Cytoskeleton Organization Regulation Of Biological Quality Cytoplasmic Vesicle Regulation Of Actin Filament-based Process Endoplasmic Reticulum-Golgi Intermediate Compartment Lumenal Side Of Endoplasmic Reticulum Membrane Regulation Of Cytoskeleton Organization Endoplasmic Reticulum Membrane Positive Regulation Of Excitatory Postsynaptic Potential Protein Transport Negative Regulation Of Organ Growth Intra-Golgi Vesicle-mediated Transport Peptide Antigen Binding Regulation Of Protein Metabolic Process Plasma Membrane Regulation Of Innate Immune Response Signaling Receptor Activator Activity Positive Regulation Of Macromolecule Biosynthetic Process Neuron Projection Organization Cytoplasm Positive Regulation Of Metabolic Process Modulation Of Chemical Synaptic Transmission Positive Regulation Of Biosynthetic Process Positive Regulation Of Multicellular Organismal Process Regulation Of Nervous System Process Modulation Of Excitatory Postsynaptic Potential Positive Regulation Of Cytokine Production Regulation Of Cellular Component Organization Membrane Regulation Of Supramolecular Fiber Organization Regulation Of Reactive Oxygen Species Metabolic Process Cellular Localization Regulation Of Intracellular Signal Transduction Intracellular Protein Localization Intracellular Protein Transport ER To Golgi Transport Vesicle Membrane Positive Regulation Of Tolerance Induction
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