CHCHD4 and HADHB

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		CHCHD4	HADHB
Description		coiled-coil-helix-coiled-coil-helix domain containing 4	hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Intermembrane Space	Nucleoplasm Mitochondrion Mitochondrial Envelope Mitochondrial Outer Membrane Mitochondrial Inner Membrane Endoplasmic Reticulum Membrane Mitochondrial Fatty Acid Beta-oxidation Multienzyme Complex Mitochondrial Nucleoid
	Molecular Function	Protein Binding Protein-disulfide Reductase Activity Oxidoreductase Activity	RNA Binding (3S)-3-hydroxyacyl-CoA Dehydrogenase (NAD+) Activity Acetyl-CoA C-acetyltransferase Activity Acetyl-CoA C-acyltransferase Activity Enoyl-CoA Hydratase Activity Protein Binding Transferase Activity Acyltransferase Activity Acyltransferase Activity, Transferring Groups Other Than Amino-acyl Groups Protein-containing Complex Binding Acetyl-CoA C-myristoyltransferase Activity LncRNA Binding
	Biological Process	Protein Transport Mitochondrial Respiratory Chain Complex Assembly Protein Import Into Mitochondrial Intermembrane Space Protein Maturation Establishment Of Protein Localization To Mitochondrion Mitochondrial Disulfide Relay System	Lipid Metabolic Process Fatty Acid Metabolic Process Fatty Acid Beta-oxidation Gene Expression Cellular Response To Lipopolysaccharide
Pathways		Mitochondrial protein import	Acyl chain remodeling of CL Beta oxidation of myristoyl-CoA to lauroyl-CoA mitochondrial fatty acid beta-oxidation of unsaturated fatty acids Beta oxidation of palmitoyl-CoA to myristoyl-CoA Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA Beta oxidation of octanoyl-CoA to hexanoyl-CoA Beta oxidation of hexanoyl-CoA to butanoyl-CoA
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Diseases
GWAS
Interacting Genes		2 interacting genes: CIAPIN1 HADHB	19 interacting genes: ALK ANXA7 APP CDC42 CDKN1A CEBPA CHCHD4 COX17 DDX17 GRB7 HSD17B10 HSPB2 RCC1 SMN1 SUOX TIMM8B TK1 TNNI3K UBC
Entrez ID		131474	3032
HPRD ID		13045	00887
Ensembl ID		ENSG00000163528	ENSG00000138029
Uniprot IDs		Q8N4Q1	F5GZQ3 P55084
PDB IDs		2K3J 2L0Y 8VGY	5ZQZ 5ZRV 6DV2
Enriched GO Terms of Interacting Partners?		Acetyl-CoA C-acetyltransferase Activity Acetyl-CoA C-myristoyltransferase Activity Mitochondrial Fatty Acid Beta-oxidation Multienzyme Complex Enoyl-CoA Hydratase Activity (3S)-3-hydroxyacyl-CoA Dehydrogenase (NAD+) Activity Acetyl-CoA C-acyltransferase Activity Mitochondrial Envelope LncRNA Binding 2 Iron, 2 Sulfur Cluster Binding Iron-sulfur Cluster Assembly Acyltransferase Activity, Transferring Groups Other Than Amino-acyl Groups Mitochondrial Nucleoid 4 Iron, 4 Sulfur Cluster Binding Fatty Acid Beta-oxidation Electron Transfer Activity Mitochondrion Fatty Acid Catabolic Process Fatty Acid Oxidation Mitochondrial Intermembrane Space Iron-sulfur Cluster Binding Lipid Oxidation	Mitochondrial Intermembrane Space
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