ANTXR2 and RAP1GDS1

		ANTXR2	RAP1GDS1
Description		ANTXR cell adhesion molecule 2	Rap1 GTPase-GDP dissociation stimulator 1
Image
GO Annotations	Cellular Component	Extracellular Region Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane External Side Of Plasma Membrane Cell Surface Endosome Membrane Membrane	Extracellular Space Nucleus Cytoplasm Mitochondrion Endoplasmic Reticulum Cytosol Extracellular Exosome
	Molecular Function	Transmembrane Signaling Receptor Activity Protein Binding Signaling Receptor Activity Metal Ion Binding	Guanyl-nucleotide Exchange Factor Activity Protein Binding GTPase Regulator Activity
	Biological Process	Single Fertilization Collagen Fibril Organization Uterus Development	Cardiac Muscle Hypertrophy Regulation Of Mitochondrion Organization Vascular Associated Smooth Muscle Contraction Myosin Filament Assembly Negative Regulation Of Endoplasmic Reticulum Calcium Ion Concentration Protein Localization To Nucleus Positive Regulation Of Mitochondrial Calcium Ion Concentration Regulation Of ERK5 Cascade CAAX-box Protein Maturation Angiotensin-activated Signaling Pathway Involved In Heart Process Regulation Of Matrix Metallopeptidase Secretion
Pathways			RHOT2 GTPase cycle RHOT1 GTPase cycle
Drugs		MDX-1303
Diseases		Infantile systemic hyalinosis and juvenile hyaline fibromatosis
GWAS		Adult body size ( 32376654) Ankylosing spondylitis ( 21743469 20062062) Bipolar disorder (inflammation and infection response interaction) ( 25781172) Carotid plaque burden ( 28282560) Childhood ALL/LBL (acute lymphoblastic leukemia/lymphoblastic lymphoma) treatment-related venous thromboembolism ( 32438682) Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Essential hypertension (time to event) ( 32589924) Hand grip strength ( 29691431) Lymphocyte count ( 27863252 32888494) Lymphocyte percentage of white cells ( 27863252 32888494) Myopia ( 27182965) Neutrophil percentage of white cells ( 27863252 32888494) Refractive error ( 32231278) Response to cognitive-behavioural therapy in major depressive disorder ( 31123309) Spherical equivalent or myopia (age of diagnosis) ( 29808027) White blood cell count ( 32888494)	Biochemical measures ( 19260141) Response to fenofibrate (total cholesterol levels) ( 27002377) Suicidality in mood disorders ( 33783297) Suicide attempt severity in mood disorders ( 33783297)
Interacting Genes		12 interacting genes: CFTR COL4A2 COL4A3 COL4A4 COL4A5 DDX10 FRAS1 LAMB1 LAMC1 LRP6 RAP1GDS1 SMAD2	27 interacting genes: ABCB7 AKT1 ANTXR2 CDC42 DIRAS1 DOC2A EGFR HRAS KIFAP3 KRAS LCOR LEF1 MBIP MED28 NRAS OGT PLEKHB1 PTPRF PUF60 RAC1 RAP1A RAP2B RHOA RNF19B RRAS2 UBC ZNF451
Entrez ID		118429	5910
HPRD ID		07452	11763
Ensembl ID		ENSG00000163297	ENSG00000138698
Uniprot IDs		A4FUA5 J3KPY9 P58335 Q32Q26	B3KNU0 P52306 Q6U7G8
PDB IDs		1SHT 1SHU 1T6B 1TZN 7N1O 8FT6 8FT8 8FZ4 8FZU 8FZV 9DOC	5XGC 5ZHX
Enriched GO Terms of Interacting Partners?		Basement Membrane Extracellular Matrix Structural Constituent Collagen Type IV Trimer Extracellular Matrix Extracellular Matrix Structural Constituent Conferring Tensile Strength Endoplasmic Reticulum Lumen Collagen-activated Tyrosine Kinase Receptor Signaling Pathway Collagen-activated Signaling Pathway Collagen Trimer Laminin-1 Complex Laminin-10 Complex Regulation Of Basement Membrane Organization Protein Complex Involved In Cell-matrix Adhesion Extracellular Structure Organization Extracellular Matrix Organization Glomerular Basement Membrane Development Positive Regulation Of Integrin-mediated Signaling Pathway Regulation Of Integrin-mediated Signaling Pathway Response To Cholesterol Developmental Process Extracellular Region Endoderm Development Endodermal Cell Differentiation Animal Organ Morphogenesis Substrate Adhesion-dependent Cell Spreading Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Response To Alcohol Laminin-8 Complex Neuronal-glial Interaction Involved In Cerebral Cortex Radial Glia Guided Migration CAAX-box Protein Maturation Enzyme-linked Receptor Protein Signaling Pathway Regulation Of Extracellular Matrix Organization Response To Transforming Growth Factor Beta Positive Regulation Of Anion Channel Activity Laminin-2 Complex Positive Regulation Of Muscle Cell Differentiation Roof Of Mouth Development Homomeric SMAD Protein Complex Regulation Of ERK5 Cascade Angiotensin-activated Signaling Pathway Involved In Heart Process Odontogenesis Anatomical Structure Formation Involved In Morphogenesis Positive Regulation Of Monoatomic Anion Transport Regulation Of Epithelial Cell Proliferation Laminin-11 Complex Zygotic Specification Of Dorsal/ventral Axis Activin Responsive Factor Complex Paraxial Mesoderm Morphogenesis	G Protein Activity GTPase Activity GDP Binding GTP Binding Small GTPase-mediated Signal Transduction Intracellular Signaling Cassette Glutamatergic Synapse Regulation Of Protein Localization To Membrane Nucleotide Binding Positive Regulation Of Intracellular Signal Transduction Regulation Of Phosphorus Metabolic Process Positive Regulation Of Protein Phosphorylation Regulation Of Cell Migration Regulation Of Protein Phosphorylation Positive Regulation Of Cell Migration Regulation Of Cell Motility Positive Regulation Of Signal Transduction Positive Regulation Of Phosphorylation Positive Regulation Of Cell Motility Endoplasmic Reticulum Membrane Regulation Of Locomotion Positive Regulation Of Locomotion Regulation Of Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane Regulation Of Phosphorylation Regulation Of Protein Localization To Cell Periphery Regulation Of Protein Modification Process Intracellular Signal Transduction Positive Regulation Of Cell Communication Positive Regulation Of Signaling Ras Protein Signal Transduction Positive Regulation Of Phosphate Metabolic Process Regulation Of Protein Localization To Synapse Regulation Of Receptor Localization To Synapse Positive Regulation Of Epithelial Cell Proliferation Cerebral Cortex Cell Migration Wnt Signaling Pathway, Planar Cell Polarity Pathway Positive Regulation Of Protein Modification Process Regulation Of Developmental Process Postsynapse Signal Transduction Positive Regulation Of Plasma Membrane Bounded Cell Projection Assembly Forebrain Radial Glial Cell Differentiation Cell Development Telencephalon Cell Migration Focal Adhesion Regulation Of Plasma Membrane Bounded Cell Projection Organization Apoptotic Process Positive Regulation Of Cell Cycle Process Cell Migration Forebrain Cell Migration
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?