GINM1 and ARID1B

		GINM1	ARID1B
Description		glycosylated integral membrane protein 1	AT-rich interaction domain 1B
Image		No pdb structure
GO Annotations	Cellular Component	Membrane	Chromatin Nucleus Nucleoplasm Cytosol Plasma Membrane SWI/SNF Complex Brahma Complex NpBAF Complex NBAF Complex BBAF Complex
	Molecular Function	Protein Binding	DNA Binding Transcription Coactivator Activity Protein Binding Nucleosome Binding
	Biological Process		Chromatin Organization Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Nervous System Development Regulation Of Mitotic Metaphase/anaphase Transition Positive Regulation Of T Cell Differentiation Positive Regulation Of Cell Differentiation Positive Regulation Of Myoblast Differentiation Transcription Initiation-coupled Chromatin Remodeling Positive Regulation Of DNA-templated Transcription Regulation Of G0 To G1 Transition Regulation Of G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Double-strand Break Repair Regulation Of Nucleotide-excision Repair
Pathways			RMTs methylate histone arginines RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known Regulation of MITF-M-dependent genes involved in pigmentation Regulation of MITF-M-dependent genes involved in pigmentation Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) Formation of the canonical BAF (cBAF) complex Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF)
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Subcortical volume (MOSTest) ( 32665545)	Allergic disease (asthma, hay fever or eczema) ( 29083406) Alzheimer's disease biomarkers ( 23419831) Calcium levels ( 24068962) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Heel bone mineral density ( 30598549) Hematocrit ( 32888494) Hemoglobin levels ( 32327693) Iris color (b* coordinate) ( 30895295) Lipoprotein (a) levels ( 26377243) Low density lipoprotein cholesterol levels ( 30498476) Multiple system atrophy (pathologically confirmed) ( 27629089) Pancreatic cancer ( 22158540) Psychosis proneness (perceptual aberration scale and revised physical anhedonia scale) ( 28525603) Pulse pressure ( 27841878) Red blood cell count ( 32888494) Sensory disturbances after bilateral sagittal split ramus osteotomy ( 23834954) Type 2 diabetes ( 29621232) Vein graft stenosis in coronary artery bypass grafting ( 25881214) Western dietary pattern ( 28644415)
Interacting Genes		3 interacting genes: ARID1B CFTR FATE1	15 interacting genes: CUL2 DCPH1 ENO1 GINM1 H2BC21 MAU2 MTHFD1L NCOA6 PLEKHG1 PYGM SMAD9 SMARCA2 SMARCA4 TNFRSF19 ZBTB2
Entrez ID		116254	57492
HPRD ID		12896	10660
Ensembl ID		ENSG00000055211	ENSG00000049618
Uniprot IDs		Q9NU53	A0A1B0GTJ8 A0A1B0GVK1 A0A3F2YNW7 A0A6Q8NVI4 H0Y7H8 Q8NFD5
PDB IDs			2CXY 2EH9
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Anion Channel Activity Positive Regulation Of Enamel Mineralization Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Positive Regulation Of Monoatomic Anion Transport Negative Regulation Of Mitochondrial Calcium Ion Concentration Bicarbonate Transmembrane Transporter Activity Intracellular PH Elevation Intracellular Monoatomic Ion Homeostasis Positive Regulation Of Tooth Mineralization Chloride Channel Inhibitor Activity Transepithelial Water Transport Intracellular Monoatomic Cation Homeostasis Amelogenesis Chloride Channel Regulator Activity Regulation Of Enamel Mineralization Membrane Hyperpolarization ATPase-coupled Inorganic Anion Transmembrane Transporter Activity BBAF Complex Regulation Of Monoatomic Anion Transport Monoatomic Ion Homeostasis Monoatomic Cation Homeostasis Epithelial Fluid Transport Golgi-associated Vesicle Membrane Brahma Complex NpBAF Complex Cellular Response To Forskolin Intracellular Chemical Homeostasis NBAF Complex Response To Forskolin Chloride Transmembrane Transporter Activity Sperm Capacitation Mitochondrial Calcium Ion Homeostasis Cellular Homeostasis Mitochondria-associated Endoplasmic Reticulum Membrane Contact Site Bicarbonate Transport Water Transport Multicellular Organismal-level Water Homeostasis Regulation Of Nucleotide-excision Repair SWI/SNF Complex Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Positive Regulation Of Ion Transmembrane Transporter Activity Cholesterol Biosynthetic Process 14-3-3 Protein Binding Fluid Transport Transepithelial Transport Nucleosome Binding Regulation Of G0 To G1 Transition Vesicle Docking Involved In Exocytosis	Nucleosome Array Spacer Activity BBAF Complex NpBAF Complex GBAF Complex NBAF Complex Regulation Of Nucleotide-excision Repair SWI/SNF Complex ATP-dependent Activity, Acting On DNA Negative Regulation Of Cell Growth Regulation Of G0 To G1 Transition Negative Regulation Of Growth Positive Regulation Of Stem Cell Population Maintenance Positive Regulation Of Myoblast Differentiation Protein Carboxyl O-methyltransferase Activity Protein-glutamate O-methyltransferase Activity Fructose 6-phosphate Aldolase Activity Regulation Of Stem Cell Population Maintenance Transcription Coactivator Activity Cohesin Loader Activity Scc2-Scc4 Cohesin Loading Complex SMC Loading Complex 10-formyltetrahydrofolate Biosynthetic Process Formate-tetrahydrofolate Ligase Activity Fructose-1-phosphatase Activity Regulation Of Myoblast Differentiation Phosphopyruvate Hydratase Complex Phosphopyruvate Hydratase Activity Nucleoplasm Glycogen Phosphorylase Activity Positive Regulation Of Glucose Mediated Signaling Pathway Formate Biosynthetic Process
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