ARID1B and MAU2

		ARID1B	MAU2
Description		AT-rich interaction domain 1B	MAU2 sister chromatid cohesion factor
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytosol Plasma Membrane SWI/SNF Complex Brahma Complex NpBAF Complex NBAF Complex BBAF Complex	Chromatin Nucleus Nucleoplasm Chromosome Nuclear Body SMC Loading Complex Scc2-Scc4 Cohesin Loading Complex
	Molecular Function	DNA Binding Transcription Coactivator Activity Protein Binding Nucleosome Binding	Protein Binding Cohesin Loader Activity
	Biological Process	Chromatin Organization Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Nervous System Development Regulation Of Mitotic Metaphase/anaphase Transition Positive Regulation Of T Cell Differentiation Positive Regulation Of Cell Differentiation Positive Regulation Of Myoblast Differentiation Transcription Initiation-coupled Chromatin Remodeling Positive Regulation Of DNA-templated Transcription Regulation Of G0 To G1 Transition Regulation Of G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Double-strand Break Repair Regulation Of Nucleotide-excision Repair	Chromosome Segregation Mitotic Sister Chromatid Cohesion Maintenance Of Mitotic Sister Chromatid Cohesion Cell Division
Pathways		RMTs methylate histone arginines RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known Regulation of MITF-M-dependent genes involved in pigmentation Regulation of MITF-M-dependent genes involved in pigmentation Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) Formation of the canonical BAF (cBAF) complex Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF)	Cohesin Loading onto Chromatin
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29083406) Alzheimer's disease biomarkers ( 23419831) Calcium levels ( 24068962) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Heel bone mineral density ( 30598549) Hematocrit ( 32888494) Hemoglobin levels ( 32327693) Iris color (b* coordinate) ( 30895295) Lipoprotein (a) levels ( 26377243) Low density lipoprotein cholesterol levels ( 30498476) Multiple system atrophy (pathologically confirmed) ( 27629089) Pancreatic cancer ( 22158540) Psychosis proneness (perceptual aberration scale and revised physical anhedonia scale) ( 28525603) Pulse pressure ( 27841878) Red blood cell count ( 32888494) Sensory disturbances after bilateral sagittal split ramus osteotomy ( 23834954) Type 2 diabetes ( 29621232) Vein graft stenosis in coronary artery bypass grafting ( 25881214) Western dietary pattern ( 28644415)	Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Bipolar II disorder ( 31043756) Brain morphology (MOSTest) ( 32665545) Estimated glomerular filtration rate ( 31451708) Fasting triglyceride levels ( 32603185) LDL cholesterol change in response to fenofibrate in statin-treated type 2 diabetes ( 28736931) Liver volume ( 34128465) Nonsyndromic cleft palate ( 31609978) Plateletcrit ( 27863252) Postprandial triglyceride levels ( 32603185) Red cell distribution width ( 32888494) Refractive error ( 32231278) Response to fenofibrate (LDL cholesterol levels) ( 27002377) Schizophrenia ( 30285260 29483656 25056061 23974872) Serum metabolite levels ( 33031748) Triglycerides ( 30275531 26780889) White blood cell count (basophil) ( 27863252)
Interacting Genes		15 interacting genes: CUL2 DCPH1 ENO1 GINM1 H2BC21 MAU2 MTHFD1L NCOA6 PLEKHG1 PYGM SMAD9 SMARCA2 SMARCA4 TNFRSF19 ZBTB2	2 interacting genes: ARID1B CLTC
Entrez ID		57492	23383
HPRD ID		10660	11117
Ensembl ID		ENSG00000049618	ENSG00000129933
Uniprot IDs		A0A1B0GTJ8 A0A1B0GVK1 A0A3F2YNW7 A0A6Q8NVI4 H0Y7H8 Q8NFD5	Q9Y6X3
PDB IDs		2CXY 2EH9
Enriched GO Terms of Interacting Partners?		Nucleosome Array Spacer Activity BBAF Complex NpBAF Complex GBAF Complex NBAF Complex Regulation Of Nucleotide-excision Repair SWI/SNF Complex ATP-dependent Activity, Acting On DNA Negative Regulation Of Cell Growth Regulation Of G0 To G1 Transition Negative Regulation Of Growth Positive Regulation Of Stem Cell Population Maintenance Positive Regulation Of Myoblast Differentiation Protein Carboxyl O-methyltransferase Activity Protein-glutamate O-methyltransferase Activity Fructose 6-phosphate Aldolase Activity Regulation Of Stem Cell Population Maintenance Transcription Coactivator Activity Cohesin Loader Activity Scc2-Scc4 Cohesin Loading Complex SMC Loading Complex 10-formyltetrahydrofolate Biosynthetic Process Formate-tetrahydrofolate Ligase Activity Fructose-1-phosphatase Activity Regulation Of Myoblast Differentiation Phosphopyruvate Hydratase Complex Phosphopyruvate Hydratase Activity Nucleoplasm Glycogen Phosphorylase Activity Positive Regulation Of Glucose Mediated Signaling Pathway Formate Biosynthetic Process	Clathrin Coat Of Trans-Golgi Network Vesicle Vesicle Uncoating Regulation Of Hyaluronan Biosynthetic Process Negative Regulation Of Hyaluronan Biosynthetic Process Clathrin Coat Clathrin Coat Of Coated Pit Clathrin Light Chain Binding Clathrin Coat Disassembly Amyloid-beta Clearance By Transcytosis Clathrin Complex BBAF Complex Transferrin Transport Regulation Of Cell Cycle Process Mitotic Spindle Microtubule Brahma Complex NBAF Complex NpBAF Complex Transcytosis Endolysosome Membrane Ubiquitin-specific Protease Binding Clathrin Coat Assembly Clathrin-coated Endocytic Vesicle Low-density Lipoprotein Particle Receptor Binding Negative Regulation Of Protein Localization To Plasma Membrane Clathrin-dependent Endocytosis Amyloid-beta Clearance Disordered Domain Specific Binding Regulation Of Cell Cycle Regulation Of Nucleotide-excision Repair Nucleosome Binding SWI/SNF Complex Protein Depolymerization Regulation Of G0 To G1 Transition Regulation Of Mitotic Spindle Organization Iron Ion Transport Regulation Of Organelle Organization Positive Regulation Of Myoblast Differentiation Transcription Initiation-coupled Chromatin Remodeling Positive Regulation Of Gene Expression, Epigenetic Receptor Internalization Clathrin-coated Endocytic Vesicle Membrane Clathrin-coated Pit Double-stranded RNA Binding Clathrin-coated Vesicle Regulation Of Myoblast Differentiation Extracellular Vesicle Regulation Of Mitotic Metaphase/anaphase Transition Retrograde Transport, Endosome To Golgi Positive Regulation Of Double-strand Break Repair Melanosome
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