MAL2 and TPD52L2

Number of citations of the paper that reports this interaction (PubMedID 11549320)
0

Data Source:
HPRD (two hybrid, in vitro)

		MAL2	TPD52L2
Description		mal, T cell differentiation protein 2	TPD52 like 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Endomembrane System Membrane Apical Plasma Membrane Membrane Raft Perinuclear Region Of Cytoplasm Extracellular Exosome	Cytoplasm Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Structural Constituent Of Myelin Sheath	RNA Binding Protein Binding Protein Homodimerization Activity
	Biological Process	Myelination	Carbohydrate Metabolic Process Regulation Of Cell Population Proliferation
Pathways
Drugs			Phenethyl Isothiocyanate
Diseases
GWAS		Aspartate aminotransferase levels ( 33547301) Blood pressure (smoking interaction) ( 25189868) Gallstone disease ( 30504769) Hippocampal atrophy ( 19668339) Osteoprotegerin levels ( 25080503)	Prostate cancer ( 23535732)
Interacting Genes		50 interacting genes: ABCG8 AQP6 ARFIP2 ARL13B ATP6V0E1 CD160 CD68 CHAF1B COQ8A CREB3 CREB3L1 ECPAS FAM3A GAD1 GAD2 GJB1 GPR152 HSFX1 HSFX2 MRM1 MTERF3 MUC1 NDRG4 NFAM1 PBX3 PIMREG PITPNC1 POLL PPP1CA PTPN9 RAB37 REEP4 RETREG3 S100B SCN3B SGK1 SH3GL1 SH3GLB1 SHMT2 SLC35H1 SUCLA2 TBRG4 THAP4 TMEM14B TPD52 TPD52L1 TPD52L2 TTPA TUBB VARS2	10 interacting genes: ABHD5 ADORA2B APP CDC42 COQ8A MAL2 SH3GLB1 TPD52 TPD52L1 TPD52L3
Entrez ID		114569	7165
HPRD ID		14351	11947
Ensembl ID		ENSG00000147676	ENSG00000101150
Uniprot IDs		Q969L2	A0A087WYR3 A0A087WZ51 O43399 Q68E05 Q6FGS1
PDB IDs
Enriched GO Terms of Interacting Partners?		Succinate Metabolic Process Gamma-aminobutyrate Shunt Glutamate Decarboxylase Activity Gamma-aminobutyric Acid Biosynthetic Process	Lysophosphatidic Acid Acyltransferase Activity Positive Regulation Of Chronic Inflammatory Response To Non-antigenic Stimulus Amyloid-beta Complex Growth Cone Lamellipodium Neuron Projection Organization Regulation Of Response To Calcium Ion Perinuclear Region Of Cytoplasm Amylin Binding Positive Regulation Of Toll Signaling Pathway Protein Homodimerization Activity Phosphatidic Acid Metabolic Process Phosphatidic Acid Biosynthetic Process Protein Localization To Vacuolar Membrane Regulation Of Chemokine Production Positive Regulation Of Interleukin-6 Production Positive Regulation Of Chemokine Production Acetylcholine Receptor Activator Activity PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Positive Regulation Of JNK Cascade Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Endothelin Receptor Signaling Pathway Involved In Heart Process Regulation Of Cytokinesis GBD Domain Binding Storage Vacuole Negative Regulation Of Triglyceride Storage Lipase Activator Activity Positive Regulation Of Membrane Tubulation Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Chronic Inflammatory Response G Protein-coupled Adenosine Receptor Activity Relaxation Of Vascular Associated Smooth Muscle Regulation Of Vesicle-mediated Transport Regulation Of Interleukin-6 Production Regulation Of Spontaneous Synaptic Transmission Positive Regulation Of Catabolic Process Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Regulation Of JNK Cascade Axon Midline Choice Point Recognition Positive Regulation Of MAPK Cascade
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