TPD52L2 and TPD52

Number of citations of the paper that reports this interaction (PubMedID 40437099)
172

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, biochemical)
HPRD (two hybrid)

		TPD52L2	TPD52
Description		TPD52 like 2	tumor protein D52
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Perinuclear Region Of Cytoplasm	Cytoplasm Endoplasmic Reticulum Perinuclear Region Of Cytoplasm
	Molecular Function	RNA Binding Protein Binding Protein Homodimerization Activity	Calcium Ion Binding Protein Binding Protein Homodimerization Activity
	Biological Process	Carbohydrate Metabolic Process Regulation Of Cell Population Proliferation	Positive Regulation Of Cell Population Proliferation Anatomical Structure Morphogenesis B Cell Differentiation Secretion
Pathways			Golgi Associated Vesicle Biogenesis
Drugs		Phenethyl Isothiocyanate
Diseases
GWAS		Prostate cancer ( 23535732)	Allergic rhinitis ( 30013184) Allergy ( 27182965) Asthma ( 34103634 31959851 31619474 31361310 29273806 27182965) Asthma (adult onset) ( 31036433) Asthma (childhood onset) ( 31036433) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Fasting glucose ( 34059833) Kawasaki disease ( 33772158) Lapatinib-induced hepatotoxicity ( 25987243) Metabolite levels (HVA/MHPG ratio) ( 23319000) Metabolite levels (Pyroglutamine) ( 23934736) Rheumatoid arthritis ( 30423114 24390342) Self-reported allergy ( 23817569)
Interacting Genes		10 interacting genes: ABHD5 ADORA2B APP CDC42 COQ8A MAL2 SH3GLB1 TPD52 TPD52L1 TPD52L3	17 interacting genes: ANXA6 AR MAL2 MAPK3 SENP2 SH3GLB1 SOCS2 SPG21 SPOP SRPK2 STUB1 THAP4 TPD52L1 TPD52L2 TPD52L3 TTPA UBC
Entrez ID		7165	7163
HPRD ID		11947	04963
Ensembl ID		ENSG00000101150	ENSG00000076554
Uniprot IDs		A0A087WYR3 A0A087WZ51 O43399 Q68E05 Q6FGS1	P55327
PDB IDs
Enriched GO Terms of Interacting Partners?		Lysophosphatidic Acid Acyltransferase Activity Positive Regulation Of Chronic Inflammatory Response To Non-antigenic Stimulus Amyloid-beta Complex Growth Cone Lamellipodium Neuron Projection Organization Regulation Of Response To Calcium Ion Perinuclear Region Of Cytoplasm Amylin Binding Positive Regulation Of Toll Signaling Pathway Protein Homodimerization Activity Phosphatidic Acid Metabolic Process Phosphatidic Acid Biosynthetic Process Protein Localization To Vacuolar Membrane Regulation Of Chemokine Production Positive Regulation Of Interleukin-6 Production Positive Regulation Of Chemokine Production Acetylcholine Receptor Activator Activity PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Positive Regulation Of JNK Cascade Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Endothelin Receptor Signaling Pathway Involved In Heart Process Regulation Of Cytokinesis GBD Domain Binding Storage Vacuole Negative Regulation Of Triglyceride Storage Lipase Activator Activity Positive Regulation Of Membrane Tubulation Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Chronic Inflammatory Response G Protein-coupled Adenosine Receptor Activity Relaxation Of Vascular Associated Smooth Muscle Regulation Of Vesicle-mediated Transport Regulation Of Interleukin-6 Production Regulation Of Spontaneous Synaptic Transmission Positive Regulation Of Catabolic Process Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Regulation Of JNK Cascade Axon Midline Choice Point Recognition Positive Regulation Of MAPK Cascade	Cytoplasm Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway ERBB Signaling Pathway Mammary Gland Alveolus Development Positive Regulation Of Macroautophagy Animal Organ Formation ERBB2 Signaling Pathway Lipid Binding Enzyme-linked Receptor Protein Signaling Pathway Regulation Of Protein Stability Protein Modification By Small Protein Conjugation Insulin-like Growth Factor Receptor Signaling Pathway Prostate Induction Male Somatic Sex Determination Protein Modification Process Positive Regulation Of Autophagy Regulation Of Macroautophagy Negative Regulation Of Establishment Of Blood-brain Barrier Post-translational Protein Modification Positive Regulation Of Chaperone-mediated Protein Complex Assembly Peroxynitrite Isomerase Activity Protein Localization To Vacuolar Membrane Response To Epidermal Growth Factor
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