TWF2 and COXFA4L3

		TWF2	COXFA4L3
Description		twinfilin actin binding protein 2	cytochrome c oxidase associated subunit FA4L3
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Actin Filament Myofibril Lamellipodium Filopodium Growth Cone Stereocilium Cell Projection Perinuclear Region Of Cytoplasm Extracellular Exosome	Nucleus Mitochondrion Respiratory Chain Complex IV
	Molecular Function	RNA Binding Actin Binding Actin Monomer Binding Protein Kinase C Binding Protein Binding ATP Binding Phosphatidylinositol-4,5-bisphosphate Binding Anion Binding Cadherin Binding Actin Filament Binding	Protein Binding
	Biological Process	Regulation Of Lamellipodium Assembly Positive Regulation Of Lamellipodium Assembly Positive Regulation Of Neuron Projection Development Cell Projection Organization Actin Filament Depolymerization Negative Regulation Of Actin Filament Polymerization Regulation Of Microvillus Length Regulation Of Actin Cytoskeleton Organization Positive Regulation Of Axon Extension Barbed-end Actin Filament Capping Cellular Response To Retinoic Acid Cellular Response To Growth Factor Stimulus	Response To Bacterium
Pathways		Sensory processing of sound by inner hair cells of the cochlea Sensory processing of sound by outer hair cells of the cochlea
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 21926972) Schizophrenia ( 23974872)
Interacting Genes		12 interacting genes: ARHGDIA CEBPA CHGB COXFA4L3 FAM107A FOXJ1 ILK MANF NISCH POT1 STAB1 TERF2IP	5 interacting genes: ABL2 FBXO7 SEMA6D TSSK3 TWF2
Entrez ID		11344	84419
HPRD ID		08464	16332
Ensembl ID		ENSG00000247596	ENSG00000166920
Uniprot IDs		Q6IBS0	Q9C002
PDB IDs		2VAC 2W0I
Enriched GO Terms of Interacting Partners?		Nuclear Telomere Cap Complex Shelterin Complex G-rich Strand Telomeric DNA Binding Telomere Capping Telomere Maintenance Via Telomerase RNA-templated DNA Biosynthetic Process Telomeric DNA Binding Telomere Maintenance Via Telomere Lengthening Intracellular Signal Transduction RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Glomerular Parietal Epithelial Cell Development Establishment Or Maintenance Of Apical/basal Cell Polarity Positive Regulation Of Central B Cell Tolerance Induction Vasoconstriction Of Artery Involved In Ischemic Response To Lowering Of Systemic Arterial Blood Pressure Negative Regulation Of Telomere Maintenance Positive Regulation Of DNA Strand Elongation Positive Regulation Of Telomeric D-loop Disassembly G-rich Single-stranded DNA Binding Positive Regulation Of Osteoblast Differentiation Response To Vitamin B2 C/EBP Complex Central Tolerance Induction Positive Regulation Of Lung Ciliated Cell Differentiation Positive Regulation Of B Cell Tolerance Induction Negative Regulation Of Germinal Center Formation Positive Regulation Of Telomeric Loop Disassembly Positive Regulation Of Telomere Maintenance Negative Regulation Of Chromosome Organization Negative Regulation Of DNA Recombination At Telomere Rho GDP-dissociation Inhibitor Activity CHOP-C/EBP Complex Protein Localization To Cell Cortex DNA Biosynthetic Process 8-hydroxy-2'-deoxyguanosine DNA Binding Telomeric G-quadruplex DNA Binding Intracellular Signaling Cassette Regulation Of Non-canonical NF-kappaB Signal Transduction Telomere Maintenance Positive Regulation Of Chromosome Organization White Fat Cell Proliferation Metanephric Part Of Ureteric Bud Development Regulation Of Telomere Maintenance Telomeric D-loop Binding Telomere Assembly Negative Regulation Of Hemopoiesis Negative Regulation Of Hematopoietic Stem Cell Proliferation Rb-E2F Complex Ciliary Basal Body Organization Single-stranded Telomeric DNA Binding Telomere Organization	Regulation Of Neuron Projection Development Regulation Of Plasma Membrane Bounded Cell Projection Organization Regulation Of Cell Projection Organization Actin Monomer Binding Manganese Ion Binding Cellular Response To Retinoic Acid Regulation Of Axon Extension Glial Cytoplasmic Inclusion Classical Lewy Body Lewy Body Corona Lewy Neurite Response To Retinoic Acid Regulation Of Axonogenesis Positive Regulation Of Neuron Projection Development Lewy Body Core Regulation Of Cell Development Positive Regulation Of Establishment Of T Cell Polarity Actin Filament Binding Magnesium Ion Binding Regulation Of Microvillus Length Anion Binding Regulation Of Establishment Of T Cell Polarity Regulation Of Cellular Component Organization Regulation Of Locomotion Negative Regulation Of Cell Development T Cell Activation Via T Cell Receptor Contact With Antigen Bound To MHC Molecule On Antigen Presenting Cell ATP Binding Phosphorylation Regulation Of Multicellular Organismal Process Regulation Of Actin Cytoskeleton Organization Regulation Of Actin Filament-based Process Protein Phosphorylation Regulation Of Autophagy Positive Regulation Of Cell Projection Organization Actin Filament Depolymerization Regulation Of Developmental Growth Regulation Of Cell Projection Size Regulation Of Neurogenesis Negative Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Smooth Muscle Cell Migration Regulation Of Multicellular Organismal Development Regulation Of Cell Growth Barbed-end Actin Filament Capping
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