CBX3 and ZNF10

Number of citations of the paper that reports this interaction (PubMedID 20176155)
0

Data Source:
BioGRID (pull down)

		CBX3	ZNF10
Description		chromobox 3	zinc finger protein 10
Image			No pdb structure
GO Annotations	Cellular Component	Chromosome, Centromeric Region Condensed Chromosome, Centromeric Region Chromosome, Telomeric Region Chromatin Euchromatin Heterochromatin Nucleus Nuclear Envelope Nuclear Inner Membrane Nucleoplasm Pericentric Heterochromatin Spindle Senescence-associated Heterochromatin Focus Chromatin Lock Complex RNA Polymerase II Transcription Regulator Complex Site Of DNA Damage	Nucleus Protein-containing Complex
	Molecular Function	Transcription Coregulator Binding Chromatin Binding Protein Binding Enzyme Binding Protein Domain Specific Binding Identical Protein Binding Histone Methyltransferase Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Chromatin Organization Chromatin Remodeling DNA Damage Response Heterochromatin Formation Negative Regulation Of DNA-templated Transcription Rhythmic Process Cellular Response To Dexamethasone Stimulus	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II
Pathways		ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression RNA Polymerase I Promoter Escape Transcriptional Regulation by E2F6	Generic Transcription Pathway
Drugs
Diseases
GWAS		Metabolite levels ( 23823483) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Refractive error ( 32231278)
Interacting Genes		42 interacting genes: ADAMTSL4 ADNP2 ARL5A ATXN7L2 AURKA AURKB BARD1 CACNB4 CBX1 CBX5 CDC42 DNMT3B DSN1 GDF15 H1-4 H3-4 H3C1 H4C1 HECW2 HIPK2 HTR2C KLF11 L3MBTL1 LAP3 LBR LIG1 MGA MIS12 MKI67 MRPL12 NSD3 PIM1 RAD54L2 SP100 STK16 TAF4 TRIM24 TRIM28 VHL ZNF10 ZNF280D ZNF496	7 interacting genes: CARD10 CBX3 GOLGA3 NDEL1 SRY TRIM24 TRIM28
Entrez ID		11335	7556
HPRD ID		05130	01923
Ensembl ID		ENSG00000122565	ENSG00000256223
Uniprot IDs		A4D177 B8ZZ43 Q13185	P21506
PDB IDs		2L11 3DM1 3KUP 3TZD 5T1I 6HW2 8JZW
Enriched GO Terms of Interacting Partners?		Chromatin Remodeling Chromatin Organization Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Nucleus Regulation Of RNA Metabolic Process DNA Binding Heterochromatin Regulation Of Mitotic Cell Cycle Chromo Shadow Domain Binding Nucleoplasm Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Chromocenter Chromosome Epigenetic Regulation Of Gene Expression Regulation Of Metabolic Process Regulation Of Transcription By RNA Polymerase II Regulation Of Mitotic Nuclear Division Regulation Of Macromolecule Metabolic Process Negative Regulation Of RNA Metabolic Process Heterochromatin Formation Regulation Of Nuclear Division Nuclear Body Regulation Of Cell Cycle Spindle Midzone MIS12/MIND Type Complex Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Kinetochore Chromosome, Centromeric Region Regulation Of Cell Cycle Process Structural Constituent Of Chromatin Negative Regulation Of Gene Expression, Epigenetic Chromosome, Telomeric Region Protein-containing Complex Chromosome Passenger Complex Attachment Of Spindle Microtubules To Kinetochore Protein-DNA Complex Assembly Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Nucleosome Assembly Negative Regulation Of Protein Export From Nucleus Regulation Of Mitotic Cell Cycle Phase Transition Protein Heterodimerization Activity Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Metabolic Process	Euchromatin Heterochromatin Chromatin Histone H3K23ac Reader Activity Chromatin Binding Perichromatin Fibrils Regulation Of Intracellular Protein Transport Convergent Extension Involved In Axis Elongation Ubiquitin-like Protein Ligase Activity Negative Regulation Of Gene Expression, Epigenetic Krueppel-associated Box Domain Binding Heterochromatin Formation Positive Regulation Of Protein Localization To Nucleus Embryonic Placenta Morphogenesis Chromo Shadow Domain Binding Regulation Of Protein Localization To Nucleus RNA Polymerase II Transcription Regulator Complex Chromosome, Centromeric Region Senescence-associated Heterochromatin Focus Chromatin Lock Complex CBM Complex Radial Glia-guided Pyramidal Neuron Migration Neurofilament Cytoskeleton Mitotic Centrosome Separation
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