LYST and MRPS31

Number of citations of the paper that reports this interaction (PubMedID 11984006)
0

Data Source:
BioGRID (two hybrid)

		LYST	MRPS31
Description		lysosomal trafficking regulator	mitochondrial ribosomal protein S31
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Microtubule Cytoskeleton	Nucleolus Mitochondrion Mitochondrial Inner Membrane Mitochondrial Small Ribosomal Subunit Ribosome Ribonucleoprotein Complex
	Molecular Function	Protein Binding	RNA Binding Structural Constituent Of Ribosome Protein Binding Protein Domain Specific Binding
	Biological Process	Lymphocyte Mediated Immunity Phagocytosis Immune Response Protein Transport Leukocyte Chemotaxis Melanosome Organization Endosome To Lysosome Transport Via Multivesicular Body Sorting Pathway Mast Cell Secretory Granule Organization Natural Killer Cell Mediated Cytotoxicity Defense Response To Bacterium Defense Response To Protozoan Pigmentation Defense Response To Virus Defense Response To Other Organism	Mitochondrial Translation
Pathways			Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination Mitochondrial ribosome-associated quality control
Drugs
Diseases		Other phagocyte defects, including the following eight diseases: Chediak-Higashi syndrome; Griscelli syndrome, type 1 (GS1); Griscelli syndrome, type 2 (GS2); Griscelli syndrome, type 3 (GS3); beta-actin deficiency; Neutrophil-specific granule deficiency; Myeloperoxidase deficiency; Glucose 6-phosphate dehydrogenase deficiency; Shwachman syndrome
GWAS		Basophil percentage of white cells ( 32888494) Lymphocyte count ( 32888494) Post bronchodilator FEV1/FVC ratio ( 26634245) Systemic lupus erythematosus ( 19838195 26502338)	Diastolic blood pressure ( 30224653) Keratoconus ( 33649486) Myeloproliferative neoplasms ( 33057200) Neutrophil percentage of granulocytes ( 27863252)
Interacting Genes		23 interacting genes: ATN1 CALM1 CELF4 CNTROB CPAP CSNK2B DNAJC14 EFS ESRRA ESS2 HGS HNRNPM KPNB1 MED12 MRPL17 MRPS31 NCDN PCBP4 TNNI3 VTA1 YWHAB YWHAQ ZNF521	3 interacting genes: EIF6 LYST STAT3
Entrez ID		1130	10240
HPRD ID		06060	10098
Ensembl ID		ENSG00000143669	ENSG00000102738
Uniprot IDs		Q99698	Q92665
PDB IDs			3J9M 6NU2 6NU3 6RW4 6RW5 6VLZ 6VMI 6ZM5 6ZM6 6ZS9 6ZSA 6ZSB 6ZSC 6ZSD 6ZSE 6ZSG 7A5F 7A5G 7A5I 7A5K 7L08 7OG4 7P2E 7PNX 7PNY 7PNZ 7PO0 7PO1 7PO2 7PO3 7QI4 7QI5 7QI6 8ANY 8CSP 8CSQ 8CSR 8CSS 8CST 8CSU 8K2A 8OIR 8OIS 8QRK 8QRL 8QRM 8QRN 8RRI 8XT0 8XT2
Enriched GO Terms of Interacting Partners?		Protein Domain Specific Binding Regulation Of Receptor Signaling Pathway Via JAK-STAT Calcium Channel Inhibitor Activity Astral Microtubule Organization Ribonucleoprotein Complex Alternative MRNA Splicing, Via Spliceosome Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Centriole Replication Negative Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Splicing Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Multivesicular Body Organization Multivesicular Body Assembly Centriole Assembly	Regulation Of Glycolytic Process Regulation Of Carbohydrate Catabolic Process Regulation Of ATP Metabolic Process Regulation Of Purine Nucleotide Metabolic Process Regulation Of Reactive Oxygen Species Metabolic Process Assembly Of Large Subunit Precursor Of Preribosome Regulation Of Generation Of Precursor Metabolites And Energy Mast Cell Secretory Granule Organization Intracellular Transport Positive Regulation Of Growth Factor Dependent Skeletal Muscle Satellite Cell Proliferation Regulation Of Myeloid Cell Differentiation Negative Regulation Of Primary MiRNA Processing Negative Regulation Of Hydrogen Peroxide Biosynthetic Process Positive Regulation Of Skeletal Muscle Cell Proliferation Cellular Localization Establishment Of Localization In Cell Lamin Filament Nuclear Transport Nucleocytoplasmic Transport Cytosolic Ribosome Assembly RNA Sequestering Activity Postsynapse To Nucleus Signaling Pathway T-helper 17 Type Immune Response Response To Peptide Hormone Negative Regulation Of Hydrogen Peroxide Metabolic Process Negative Regulation Of 3'-UTR-mediated MRNA Stabilization Interleukin-23-mediated Signaling Pathway Regulation Of Small Molecule Metabolic Process Endosome To Lysosome Transport Via Multivesicular Body Sorting Pathway Interleukin-11-mediated Signaling Pathway Interleukin-9-mediated Signaling Pathway Cellular Response To Interleukin-17 Negative Regulation Of MiRNA Processing CCR5 Chemokine Receptor Binding Interleukin-10-mediated Signaling Pathway Cellular Response To Leptin Stimulus Positive Regulation Of Extracellular Matrix Disassembly Retinal Rod Cell Differentiation Interleukin-15-mediated Signaling Pathway Negative Regulation Of Inflammatory Response To Wounding Primary MiRNA Binding Leptin-mediated Signaling Pathway Regulation Of Hemopoiesis Ribosomal Subunit Export From Nucleus Negative Regulation Of Neuron Migration Ribosomal Large Subunit Binding Regulation Of Hydrogen Peroxide Metabolic Process Negative Regulation Of MiRNA-mediated Gene Silencing Regulation Of MiRNA Processing Growth Hormone Receptor Signaling Pathway Via JAK-STAT
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