NMU and KRTAP10-6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		NMU	KRTAP10-6
Description		neuromedin U	keratin associated protein 10-6
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Terminal Bouton	Cytosol Intermediate Filament Keratin Filament
	Molecular Function	Signaling Receptor Binding Protein Binding Type 1 Neuromedin U Receptor Binding Type 2 Neuromedin U Receptor Binding Neuromedin U Receptor Binding	Protein Binding
	Biological Process	Temperature Homeostasis Gastric Acid Secretion Positive Regulation Of Systemic Arterial Blood Pressure Regulation Of Smooth Muscle Contraction G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Neuropeptide Signaling Pathway Photoperiodism Positive Regulation Of Heart Rate Positive Regulation Of Heat Generation Eating Behavior Regulation Of Circadian Sleep/wake Cycle, Sleep Positive Regulation Of Smooth Muscle Contraction Positive Regulation Of Hormone Secretion Positive Regulation Of Synaptic Transmission Regulation Of Feeding Behavior Negative Regulation Of Gastric Acid Secretion Energy Homeostasis Negative Regulation Of Gastric Emptying Positive Regulation Of Stomach Fundus Smooth Muscle Contraction Positive Regulation Of Prolactin Secretion Negative Regulation Of Eating Behavior Positive Regulation Of Sensory Perception Of Pain Negative Regulation Of Feeding Behavior Regulation Of Grooming Behavior
Pathways		Peptide ligand-binding receptors G alpha (q) signalling events G alpha (i) signalling events	Keratinization
Drugs
Diseases
GWAS		Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Daytime sleep phenotypes ( 27126917) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) Subcortical volume (MOSTest) ( 32665545) Urinary albumin excretion ( 30220432 32277301) Urinary albumin-to-creatinine ratio ( 31511532 31630189) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172 26426971) Waist-to-hip ratio adjusted for BMI x sex interaction ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971) Waist-to-hip ratio adjusted for body mass index ( 25673412)
Interacting Genes		16 interacting genes: CYSRT1 DCDC2 KRT34 KRTAP1-1 KRTAP1-3 KRTAP1-5 KRTAP10-6 KRTAP12-3 KRTAP17-1 KRTAP5-9 NBPF19 NMUR1 NMUR2 NOTCH2NLA SNTA1 TNS2	87 interacting genes: ADAMTSL3 AVPI1 CLK1 CLK4 DHX57 DKK2 FOXD4 HAND1 HHEX HOXB5 KIAA0040 KIF9 KRTAP10-1 KRTAP10-5 KRTAP4-11 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-2 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-9 KRTAP9-8 LCE1A LCE1B LCE1D LCE1E LCE1F LCE2A LCE2B LCE2C LCE2D LCE3B LCE3C LCE3D LCE3E LCE4A LCE5A MOBP MT1B NAA10 NAXD NKD1 NMU NOL12 NPDC1 PBXIP1 PIN1 RSPO2 SLC33A2 SNIP1 SPATA3 STRA6 VASN WT1 YTHDC1 ZBTB24 ZC3HAV1 ZIM2 ZNF114 ZNF138 ZNF155 ZNF169 ZNF221 ZNF239 ZNF264 ZNF280C ZNF302 ZNF319 ZNF418 ZNF440 ZNF479 ZNF490 ZNF543 ZNF563 ZNF595 ZNF600 ZNF669 ZNF672 ZNF679 ZNF696 ZNF774 ZNF776 ZNF792 ZNHIT1
Entrez ID		10874	386674
HPRD ID		05485	11192
Ensembl ID		ENSG00000109255	ENSG00000188155
Uniprot IDs		A0A0B4J202 A0A250SH36 E9PDJ7 P48645 Q86WB6	P60371
PDB IDs		7W53 7W55 7XK8
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament Neuromedin U Receptor Activity Neuromedin U Binding Neuropeptide Receptor Activity Epidermis Development Structural Constituent Of Skin Epidermis Positive Regulation Of Calcium-mediated Signaling	Keratinization Epidermis Development DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Intermediate Filament Tissue Development Zinc Ion Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA Binding Regulation Of Transcription By RNA Polymerase II Keratin Filament Hair Cycle Regulation Of DNA-templated Transcription Regulation Of RNA Metabolic Process Regulation Of RNA Biosynthetic Process Protein Binding Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Gene Expression Positive Regulation Of Wnt Signaling Pathway Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Metal Ion Binding Diaphragm Development Cartilage Morphogenesis Regulation Of Macromolecule Metabolic Process
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