PGRMC1 and CIAO1

Number of citations of the paper that reports this interaction (PubMedID 37689310)
63

Data Source:
BioGRID (two hybrid, proximity labelling technology)

		PGRMC1	CIAO1
Description		progesterone receptor membrane component 1	cytosolic iron-sulfur assembly component 1
Image
GO Annotations	Cellular Component	Extracellular Region Mitochondrion Mitochondrial Outer Membrane Endoplasmic Reticulum Plasma Membrane Endomembrane System Membrane Smooth Endoplasmic Reticulum Membrane Specific Granule Membrane Neuron Projection Neuronal Cell Body Cell Body Synapse	Cytoplasm MMXD Complex Cytosolic [4Fe-4S] Assembly Targeting Complex
	Molecular Function	Amyloid-beta Binding Steroid Binding Protein Binding Lipid Binding Heme Binding Protein Homodimerization Activity Metal Ion Binding	Protein Binding
	Biological Process	Heme Biosynthetic Process Axon Guidance Memory Associative Learning Modification Of Synaptic Structure Positive Regulation Of Lipoprotein Transport Positive Regulation Of Protein Localization To Plasma Membrane Negative Regulation Of Synapse Organization	Regulation Of Transcription By RNA Polymerase II Chromosome Segregation Iron-sulfur Cluster Assembly Protein Maturation
Pathways		Neutrophil degranulation	Cytosolic iron-sulfur cluster assembly
Drugs		Dextromethorphan Nortriptyline Sertraline
Diseases
GWAS		Hodgkin's lymphoma ( 34216518)
Interacting Genes		21 interacting genes: BIK CAMLG CCDC134 CENPU CIAO1 CREB3L1 DEFB124 EVI2B GET3 GLP1R GOLM1 KASH5 KCNE5 LINC00632 MTNR1A MX1 PAM16 SCAP SGTB TMEM213 ZNF71	16 interacting genes: CCDC7 CIAO2A CIAO2B GOLM1 HAUS3 MEOX1 MEOX2 PGRMC1 RGS2 SHISA6 SLC4A7 SRPK1 TCP10L TOP3B UBC WT1
Entrez ID		10857	9391
HPRD ID		02338	16057
Ensembl ID		ENSG00000101856	ENSG00000144021
Uniprot IDs		O00264 Q6IB11	O76071
PDB IDs		4X8Y	3FM0
Enriched GO Terms of Interacting Partners?		GET Complex	Somite Specification Chromosome Segregation Cytosolic [4Fe-4S] Assembly Targeting Complex Segment Specification Somite Development
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