DRAP1 and TAF9B

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid, two hybrid, two hybrid)
HPRD (two hybrid)

		DRAP1	TAF9B
Description		DR1 associated protein 1	TATA-box binding protein associated factor 9b
Image
GO Annotations	Cellular Component	Nucleus Negative Cofactor 2 Complex RNA Polymerase II Transcription Regulator Complex	Nucleus Nucleoplasm Transcription Factor TFIID Complex Transcription Factor TFTC Complex
	Molecular Function	Core Promoter Sequence-specific DNA Binding RNA Polymerase II General Transcription Initiation Factor Binding DNA Binding Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity TBP-class Protein Binding Identical Protein Binding Protein Heterodimerization Activity	Transcription Corepressor Activity Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity Protein Heterodimerization Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II	Negative Regulation Of Transcription By RNA Polymerase II DNA-templated Transcription Initiation Transcription By RNA Polymerase II Positive Regulation Of Cell Growth Negative Regulation Of Apoptotic Process Protein Stabilization Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator
Pathways		Signaling by NODAL Signaling by Activin	HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome Ub-specific processing proteases RNA Polymerase II Pre-transcription Events Regulation of TP53 Activity through Phosphorylation RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Asthma ( 31959851) Eosinophil percentage of granulocytes ( 27863252) Multiple sclerosis ( 31604244) Neutrophil percentage of granulocytes ( 27863252) Severe influenza A (H1N1) infection ( 26379185)	Potassium levels ( 29403010)
Interacting Genes		31 interacting genes: APP ARHGEF10L CDKN2C DNAJB11 DR1 FBXO7 FEZ1 FEZ2 FOXH1 GTF2B LMO2 LNX1 LNX2 MCRS1 MORF4L1 NCK2 NFYB PICK1 PIK3R3 PLEKHF2 POLE3 RPL9 SDCBP SRPK2 TAF9 TAF9B TBP TK1 TNFRSF14 TTF2 ZEB1	8 interacting genes: APP DRAP1 FBXO7 H3-4 RUNX1T1 SS18L1 TP53 TRIM15
Entrez ID		10589	51616
HPRD ID		03796	06739
Ensembl ID		ENSG00000175550	ENSG00000187325
Uniprot IDs		Q14919	Q9HBM6
PDB IDs		1JFI	7KTR 7KTS
Enriched GO Terms of Interacting Partners?		RNA Polymerase II General Transcription Initiation Factor Activity Protein Heterodimerization Activity Transcription Factor TFIID Complex DNA-binding Transcription Factor Binding RNA Polymerase II Preinitiation Complex Assembly Transcription Preinitiation Complex Assembly DNA-templated Transcription Initiation Regulation Of Intrinsic Apoptotic Signaling Pathway Protein-DNA Complex Assembly Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Metabolic Process Regulation Of RNA Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Biosynthetic Process Protein-containing Complex Assembly Regulation Of Cellular Response To Stress Regulation Of Receptor Internalization Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Transcription By RNA Polymerase II ATAC Complex Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Negative Regulation Of Autophagosome Assembly Positive Regulation Of RNA Biosynthetic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Nucleus Positive Regulation Of DNA-templated Transcription Regulation Of Cell Cycle Nucleic Acid Metabolic Process Transcription Factor TFTC Complex Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Protein-containing Complex Organization Chromatin Organization Regulation Of Apoptotic Signaling Pathway RNA Polymerase II Core Promoter Sequence-specific DNA Binding Regulation Of Metabolic Process Cytoskeletal Anchor Activity Nucleobase-containing Compound Biosynthetic Process Negative Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of RNA Metabolic Process Chromatin Remodeling TBP-class Protein Binding Regulation Of Gene Expression Negative Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Receptor Internalization BHLH Transcription Factor Binding Negative Regulation Of Intrinsic Apoptotic Signaling Pathway Transcription Cis-regulatory Region Binding Positive Regulation Of Macromolecule Metabolic Process	Protein Heterodimerization Activity Regulation Of Cell Differentiation Core Promoter Sequence-specific DNA Binding Molecular Function Activator Activity Regulation Of Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Gene Expression, Epigenetic Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Neuron Apoptotic Process Chromatin Organization Regulation Of Developmental Process Regulation Of Response To Calcium Ion Positive Regulation Of Neuron Apoptotic Process Regulation Of Carbohydrate Catabolic Process Amylin Binding Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Reactive Oxygen Species Metabolic Process Dendrite Development Nucleus Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Mitophagy Negative Regulation Of Helicase Activity Regulation Of Autophagy Of Mitochondrion Negative Regulation Of G1 To G0 Transition Negative Regulation Of Cell Cycle G1/S Phase Transition Glial Cytoplasmic Inclusion Classical Lewy Body Lewy Body Corona Lewy Neurite Autophagy Of Mitochondrion Regulation Of MiRNA Transcription Acetylcholine Receptor Activator Activity Protein-folding Chaperone Binding PTB Domain Binding Regulation Of RNA Metabolic Process Collateral Sprouting In Absence Of Injury Regulation Of Protein Import DNA Binding Regulation Of Non-canonical NF-kappaB Signal Transduction Regulation Of DNA-templated Transcription Regulation Of MiRNA Metabolic Process Regulation Of RNA Biosynthetic Process Regulation Of Purine Nucleotide Metabolic Process Endosome To Plasma Membrane Transport Vesicle Protein Tetramerization Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Regulation Of Mitotic Cell Cycle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?