CXCL13 and PF4V1

Number of citations of the paper that reports this interaction (PubMedID 28381538)
0

Data Source:
BioGRID (pull down)

		CXCL13	PF4V1
Description		C-X-C motif chemokine ligand 13	platelet factor 4 variant 1
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Extracellular Region Extracellular Space
	Molecular Function	Cytokine Activity Chemokine Activity Heparin Binding Fibroblast Growth Factor Binding CXCR5 Chemokine Receptor Binding CCR10 Chemokine Receptor Binding CXCR Chemokine Receptor Binding Receptor Ligand Activity CXCR3 Chemokine Receptor Binding	Cytokine Activity Protein Binding Chemokine Activity Heparin Binding CXCR Chemokine Receptor Binding
	Biological Process	Germinal Center Formation Lymphocyte Chemotaxis Across High Endothelial Venule Chronic Inflammatory Response Regulation Of Humoral Immune Response Chemotaxis Defense Response Inflammatory Response Immune Response Cell Surface Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Cell-cell Signaling Positive Regulation Of T Cell Chemotaxis Neutrophil Chemotaxis Killing Of Cells Of Another Organism Regulation Of Rap Protein Signal Transduction Positive Regulation Of Integrin Activation Positive Regulation Of Cell-cell Adhesion Mediated By Integrin B Cell Chemotaxis Endothelial Cell Chemotaxis To Fibroblast Growth Factor Defense Response To Bacterium Regulation Of Angiogenesis Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Chemokine-mediated Signaling Pathway Cellular Response To Lipopolysaccharide Negative Regulation Of Endothelial Cell Chemotaxis To Fibroblast Growth Factor	Chemotaxis Defense Response Inflammatory Response Immune Response Signal Transduction Neutrophil Chemotaxis Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Cellular Response To Lipopolysaccharide
Pathways		Chemokine receptors bind chemokines G alpha (i) signalling events	Common Pathway of Fibrin Clot Formation Cell surface interactions at the vascular wall
Drugs
Diseases
GWAS		Cardiac Troponin-T levels ( 23247143) Diffusing capacity of carbon monoxide ( 30694715) Rheumatoid arthritis ( 32723749) Tonsillectomy ( 27182965 28928442) Waist circumference adjusted for body mass index ( 28552196)	Inflammatory bowel disease ( 23128233)
Interacting Genes		11 interacting genes: ACKR4 CCL19 CCL21 CCL28 CCL4L1 CCR10 CXCR3 CXCR5 EEF1G FGF2 PF4V1	15 interacting genes: CCL11 CCL19 CCL21 CCL22 CCL25 CCL26 CCL27 CCL28 CCL4L1 CXCL10 CXCL11 CXCL12 CXCL13 XCL1 XCL2
Entrez ID		10563	5197
HPRD ID		05513	01427
Ensembl ID		ENSG00000156234	ENSG00000109272
Uniprot IDs		O43927 Q53X90	P10720
PDB IDs		5CBA 5CBE 6VGJ 7JNY	4HSV
Enriched GO Terms of Interacting Partners?		Chemotaxis Locomotion Cell Chemotaxis Chemokine-mediated Signaling Pathway Leukocyte Chemotaxis Cell Migration Cell Motility Leukocyte Migration Chemokine Activity Granulocyte Chemotaxis C-C Chemokine Binding C-C Chemokine Receptor Activity Cytokine-mediated Signaling Pathway Cytokine Activity Granulocyte Migration Immune Response Chemokine Binding Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Myeloid Leukocyte Migration Positive Regulation Of Cytosolic Calcium Ion Concentration Chemokine Receptor Binding Antimicrobial Humoral Response Immune System Process G Protein-coupled Receptor Signaling Pathway Eosinophil Chemotaxis Eosinophil Migration Humoral Immune Response Chemokine Receptor Activity Inflammatory Response CCR7 Chemokine Receptor Binding CCR Chemokine Receptor Binding Regulation Of Sequestering Of Calcium Ion Regulation Of Dendritic Cell Dendrite Assembly Positive Regulation Of Chemotaxis Negative Regulation Of Leukocyte Tethering Or Rolling Calcium-mediated Signaling Positive Regulation Of Phospholipase C/protein Kinase C Signal Transduction Cell Surface Receptor Signaling Pathway Release Of Sequestered Calcium Ion Into Cytosol Negative Regulation Of Sequestering Of Calcium Ion Regulation Of Chemotaxis Signal Transduction Positive Regulation Of Dendritic Cell Antigen Processing And Presentation Regulation Of Leukocyte Migration C-X-C Chemokine Receptor Activity Establishment Of T Cell Polarity Negative Regulation Of Cellular Extravasation Regulation Of Cell Migration Negative Regulation Of Dendritic Cell Apoptotic Process Regulation Of Cell Motility	Chemokine Activity Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Antimicrobial Humoral Response Cell Chemotaxis Cytokine Activity Chemokine-mediated Signaling Pathway Leukocyte Chemotaxis Humoral Immune Response Granulocyte Chemotaxis Chemotaxis Locomotion Leukocyte Migration Granulocyte Migration Killing Of Cells Of Another Organism Myeloid Leukocyte Migration CCR Chemokine Receptor Binding Cell Killing Defense Response To Symbiont Defense Response To Other Organism Chemokine Receptor Binding Inflammatory Response Cell Migration Cytokine-mediated Signaling Pathway Cell Motility Response To Other Organism Immune Response Eosinophil Chemotaxis Eosinophil Migration Response To External Biotic Stimulus Defense Response Extracellular Space G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cell Migration Positive Regulation Of Cell Motility Positive Regulation Of Locomotion Immune System Process Regulation Of Cell Migration Regulation Of Cell Motility Mononuclear Cell Migration Regulation Of Locomotion Extracellular Region Lymphocyte Chemotaxis CXCR Chemokine Receptor Binding Negative Regulation Of Leukocyte Tethering Or Rolling Lymphocyte Migration Regulation Of Leukocyte Migration Response To Stress Positive Regulation Of Chemotaxis Negative Regulation Of Cellular Extravasation Cell Surface Receptor Signaling Pathway
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