PF4V1

Description		platelet factor 4 variant 1
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space
	Molecular Function	Cytokine Activity Protein Binding Chemokine Activity Heparin Binding CXCR Chemokine Receptor Binding
	Biological Process	Chemotaxis Defense Response Inflammatory Response Immune Response Signal Transduction Neutrophil Chemotaxis Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Cellular Response To Lipopolysaccharide
Pathways		Common Pathway of Fibrin Clot Formation Cell surface interactions at the vascular wall
Drugs
Diseases
GWAS		Inflammatory bowel disease ( 23128233)
Novel Interacting Genes		15 novel interacting genes: CCL11 CCL19 CCL21 CCL22 CCL25 CCL26 CCL27 CCL28 CCL4L1 CXCL10 CXCL11 CXCL12 CXCL13 XCL1 XCL2
Interacting Genes		15 interacting genes: CCL11 CCL19 CCL21 CCL22 CCL25 CCL26 CCL27 CCL28 CCL4L1 CXCL10 CXCL11 CXCL12 CXCL13 XCL1 XCL2
Entrez ID		5197
HPRD ID		01427
Ensembl ID		ENSG00000109272
Uniprot IDs		P10720
PDB IDs		4HSV
Enriched GO Terms of Interacting Partners?		Chemokine Activity Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Antimicrobial Humoral Response Cell Chemotaxis Cytokine Activity Chemokine-mediated Signaling Pathway Leukocyte Chemotaxis Humoral Immune Response Granulocyte Chemotaxis Chemotaxis Locomotion Leukocyte Migration Granulocyte Migration Killing Of Cells Of Another Organism Myeloid Leukocyte Migration CCR Chemokine Receptor Binding Cell Killing Defense Response To Symbiont Defense Response To Other Organism Chemokine Receptor Binding Inflammatory Response Cell Migration Cytokine-mediated Signaling Pathway Cell Motility Response To Other Organism Immune Response Eosinophil Chemotaxis Eosinophil Migration Response To External Biotic Stimulus Defense Response Extracellular Space G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cell Migration Positive Regulation Of Cell Motility Positive Regulation Of Locomotion Immune System Process Regulation Of Cell Migration Regulation Of Cell Motility Mononuclear Cell Migration Regulation Of Locomotion Extracellular Region Lymphocyte Chemotaxis CXCR Chemokine Receptor Binding Negative Regulation Of Leukocyte Tethering Or Rolling Lymphocyte Migration Regulation Of Leukocyte Migration Response To Stress Positive Regulation Of Chemotaxis Negative Regulation Of Cellular Extravasation Cell Surface Receptor Signaling Pathway
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