WFDC2 and FKBP7

Number of citations of the paper that reports this interaction (PubMedID 33961781)
97

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		WFDC2	FKBP7
Description		WAP four-disulfide core domain 2	FKBP prolyl isomerase 7
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Extracellular Exosome	Endoplasmic Reticulum Endoplasmic Reticulum Lumen
	Molecular Function	Endopeptidase Inhibitor Activity Serine-type Endopeptidase Inhibitor Activity Cysteine-type Endopeptidase Inhibitor Activity Protein Binding Aspartic-type Endopeptidase Inhibitor Activity Peptidase Inhibitor Activity	Peptidyl-prolyl Cis-trans Isomerase Activity Calcium Ion Binding Protein Binding FK506 Binding Isomerase Activity Metal Ion Binding
	Biological Process	Proteolysis Spermatogenesis Antibacterial Humoral Response Innate Immune Response
Pathways		Formation of the nephric duct
Drugs
Diseases
GWAS		Brain structure ( 20171287)	Alanine aminotransferase levels ( 33547301) Appendicular lean mass ( 33097823) Aspartate aminotransferase levels ( 33547301) Atrial fibrillation ( 30061737) Blood protein levels ( 30072576) Rapid functional decline in sporadic amyotrophic lateral sclerosis ( 26746183) Refractive error ( 32231278)
Interacting Genes		17 interacting genes: ARL13B CD40 CD79A COQ9 CPLX4 CREB3L1 CYB5R3 FAM209A FKBP7 GORAB LMNA PANX1 PLS3 PTN SLC22A23 STOM TMX2	112 interacting genes: ABHD16A ADGRE2 ADIPOQ AGPS AP1M1 APOD ASPH BET1 BMP10 BRICD5 C3orf52 CD81 CDIPT CDS2 CERCAM CFTR CIAO2A CLCA4 CLDN19 CNIH1 CTSA CXCL16 CYB561D2 CYB5B DIABLO ERMP1 FAM3C FARS2 GET3 H4C7 HHATL HMOX1 HSBP1L1 HTATIP2 IER3 IFITM3 IFT70A IFT70B IGFBP5 IRF2 JOSD2 LAT LNPEP MAN2B2 MIEF2 MRM1 NFU1 NKG7 NPFFR2 OCIAD1 OXNAD1 PBX3 PCYT1A PDE11A PEX16 PEX19 PLLP PLP1 PLP2 PLPP6 PPIF PRMT6 PTCD1 PTPN9 RBFA RBM45 RPRM RUSF1 SELENOK SERP1 SGTA SLC30A3 SLC38A7 SLC7A14 SNX1 SNX12 STATH STX7 STX8 SUCLA2 TARS2 TCP11X2 TECR TF THAP4 THSD7B TMEM108 TMEM120B TMEM147 TMEM14A TMEM229B TMEM239 TMEM54 TMEM86A TMEM86B TMEM97 TRAM1L1 TSPAN2 TSPO2 TTPA TXNDC12 UBIAD1 UBQLN4 UNC93B1 UPK1B UPK2 VSTM4 WFDC2 WIPI2 YIPF4 YIPF6 ZFPL1
Entrez ID		10406	51661
HPRD ID		11684	08451
Ensembl ID		ENSG00000101443	ENSG00000079150
Uniprot IDs		A0A384MTN6 Q14508	B4DRE2 Q9Y680
PDB IDs
Enriched GO Terms of Interacting Partners?			Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Protein Binding Chloride Channel Inhibitor Activity Regulation Of Cellular Localization Cellular Localization Protein Insertion Into ER Membrane Transferrin Receptor Binding Alkenylglycerophosphocholine Hydrolase Activity Lysosome Peroxisome Membrane Biogenesis Intraciliary Transport Particle B Binding Cholesterol Binding Establishment Of Localization In Cell
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