SPRY3 and SLC39A7

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SPRY3	SLC39A7
Description		sprouty RTK signaling antagonist 3	solute carrier family 39 member 7
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Membrane	Nucleoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Membrane
	Molecular Function	Protein Binding	Zinc Ion Transmembrane Transporter Activity Protein Binding Metal Ion Transmembrane Transporter Activity
	Biological Process	Nervous System Development Regulation Of Signal Transduction Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Negative Regulation Of MAPK Cascade Negative Regulation Of Ras Protein Signal Transduction Animal Organ Development Negative Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Neuron Projection Arborization	Monoatomic Ion Transport Zinc Ion Transport Intracellular Zinc Ion Homeostasis Metal Ion Transport B Cell Differentiation Transmembrane Transport Zinc Ion Transmembrane Transport Skin Epidermis Development Regulation Of Ferroptosis
Pathways			Zinc influx into cells by the SLC39 gene family
Drugs
Diseases
GWAS		Idiopathic osteonecrosis of the femoral head ( 28000841)
Interacting Genes		27 interacting genes: AQP1 BEX2 CATSPER1 CHRD CREB5 GNE GPSM3 HOXA1 HR KPRP KRT34 LCE1A LCE1B LCE1F LCE2B LCE3A LCE3D LCE3E MAPKBP1 MEOX2 NEK6 R3HDM2 SLC39A7 VSNL1 ZDHHC17 ZNF587 ZNF655	30 interacting genes: AQP6 BIK CLCA4 CRCT1 ERCC6 GJA8 KCNF1 KRTAP1-3 KRTAP5-7 KRTAP9-2 LCE1A LCE1C LCE1F LCE2C LCE2D LCE4A LCE5A LELP1 RGS17 RSPO2 SHISAL1 SLC34A2 SMCP SPRY3 STARD3 TMEM14B TNFRSF10D UNC93A WFDC12 YY1
Entrez ID		10251	7922
HPRD ID		03917	09028
Ensembl ID		ENSG00000168939	ENSG00000112473
Uniprot IDs		O43610 Q6ZUP3	A0A024RCX7 B4DZZ8 Q92504
PDB IDs			8GZE
Enriched GO Terms of Interacting Partners?		Epidermis Development Keratinization Tissue Development	Keratinization Epidermis Development Tissue Development
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