TOM1L1 and PELP1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		TOM1L1	PELP1
Description		target of myb1 like 1 membrane trafficking protein	proline, glutamate and leucine rich protein 1
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GO Annotations	Cellular Component	Cytoplasm Lysosome Endosome Golgi Apparatus Golgi Stack Cytosol Endosome Membrane Membrane Extracellular Exosome	Euchromatin Nucleus Nucleoplasm Nucleolus Cytoplasm Membrane MLL1 Complex
	Molecular Function	Protein Binding SH3 Domain Binding Protein Kinase Binding Clathrin Binding Protein Kinase Activator Activity Phosphatidylinositol Binding Ubiquitin Binding	Chromatin Binding RNA Binding Protein Binding SUMO Binding
	Biological Process	Signal Transduction Protein Transport Positive Regulation Of Protein Autophosphorylation Activation Of Protein Kinase Activity Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Negative Regulation Of Mitotic Nuclear Division Regulation Of DNA Biosynthetic Process	RRNA Processing Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Estrogen Stimulus
Pathways			Major pathway of rRNA processing in the nucleolus and cytosol PTK6 Expression
Drugs
Diseases
GWAS		Carotid intima media thickness x smoking interaction ( 32117412) Metabolite levels ( 23823483) Obesity-related traits ( 23251661) Photic sneeze reflex ( 27182965) Systolic blood pressure ( 34074324) Urinary albumin-to-creatinine ratio ( 32600054)	Eosinophil count ( 29403010)
Interacting Genes		29 interacting genes: AMFR CCDC47 CELF1 COPS7A CWF19L1 DNAJB13 FYN GLUD2 GRB2 GSN HGS HNRNPH1 MAP3K3 NDC80 NOMO1 PDPN PELP1 PHYH PIK3R1 PWP2 RAB18 TASOR TOLLIP TSG101 TUBA1B UBC UBXN4 VAV2 VCP	28 interacting genes: AR BAG6 BCAS3 BLOC1S1 CREBBP EP300 ESR1 ESR2 H1-1 H2AC20 H2BC21 H3-3A H4C1 HGS LAS1L NFKB1 NR3C1 PTEN RB1 SENP3 SMAD9 SNCA SRC STAT3 SUMO2 TOM1L1 TP53 USP7
Entrez ID		10040	27043
HPRD ID		05266	10144
Ensembl ID		ENSG00000141198	ENSG00000141456
Uniprot IDs		O75674	B4DEX7 B4DR36 C9JFV4 E7EV54 Q8IZL8
PDB IDs		3RRU	7UWF 8FL2 8FL3 8FL4
Enriched GO Terms of Interacting Partners?		BAT3 Complex Binding ERAD Pathway Proteolysis Involved In Protein Catabolic Process Cytosol Ubiquitin Binding Response To Endoplasmic Reticulum Stress Neurotrophin TRKA Receptor Binding Endosome Transport Via Multivesicular Body Sorting Pathway Intracellular Signaling Cassette Derlin-1 Retrotranslocation Complex Phosphotyrosine Residue Binding Multivesicular Body Sorting Pathway Intracellular Signal Transduction Multi-pass Transmembrane Protein Insertion Into ER Membrane Multi-pass Translocon Complex Ubiquitin Protein Ligase Binding SUMO Binding Catabolic Process Insulin Receptor Substrate Binding Macromolecule Catabolic Process Modification-dependent Protein Catabolic Process Transmembrane Receptor Protein Tyrosine Kinase Adaptor Activity Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Positive Regulation Of Exosomal Secretion Phosphatidylinositol 3-kinase Binding Ubiquitin-specific Protease Binding Regulation Of Exosomal Secretion Protein-folding Chaperone Binding Macromolecule Metabolic Process Proteolysis Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Regulation Of Protein Modification Process Cell Activation Protein Phosphatase Binding RNA Binding Regulation Of Post-translational Protein Modification Fc Receptor Mediated Stimulatory Signaling Pathway Ubiquitin-like Protein Ligase Binding Protein Binding Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Endoplasmic Reticulum Membrane Proteasomal Protein Catabolic Process Vascular Endothelial Growth Factor Receptor Signaling Pathway Ephrin Receptor Binding Fc-gamma Receptor Signaling Pathway Cellular Response To Glycine Response To Singlet Oxygen Epidermal Growth Factor Receptor Binding COP9 Signalosome Positive Regulation Of Cellular Component Biogenesis	Transcription Coactivator Binding Negative Regulation Of Macromolecule Metabolic Process Chromatin Organization Negative Regulation Of Metabolic Process Estrogen Response Element Binding Positive Regulation Of Transcription By RNA Polymerase II Chromatin Transcription Regulator Complex Chromatin Remodeling Peptidyl-lysine Acetylation Regulation Of Macromolecule Metabolic Process Positive Regulation Of Metabolic Process Regulation Of MiRNA Metabolic Process Nucleoplasm Positive Regulation Of Macromolecule Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II Nucleus Intracellular Signal Transduction Nuclear Receptor Activity Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Metabolic Process Regulation Of Small Molecule Metabolic Process Cellular Response To Hormone Stimulus Regulation Of Primary Metabolic Process Positive Regulation Of MiRNA Metabolic Process Positive Regulation Of Biosynthetic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Protein Stability Steroid Binding Regulation Of MiRNA Transcription Steroid Hormone Receptor Signaling Pathway Nuclear Receptor-mediated Steroid Hormone Signaling Pathway DNA Binding Enzyme Binding Regulation Of Transcription By RNA Polymerase II Protein-containing Complex Positive Regulation Of RNA Metabolic Process Regulation Of Phosphorus Metabolic Process Protein Acetylation Structural Constituent Of Chromatin Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of DNA-templated Transcription Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of RNA Biosynthetic Process Response To Hormone Negative Regulation Of Biosynthetic Process
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