TOM1L1 and UBXN4

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		TOM1L1	UBXN4
Description		target of myb1 like 1 membrane trafficking protein	UBX domain protein 4
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GO Annotations	Cellular Component	Cytoplasm Lysosome Endosome Golgi Apparatus Golgi Stack Cytosol Endosome Membrane Membrane Extracellular Exosome	Nucleus Nuclear Envelope Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Membrane
	Molecular Function	Protein Binding SH3 Domain Binding Protein Kinase Binding Clathrin Binding Protein Kinase Activator Activity Phosphatidylinositol Binding Ubiquitin Binding	Protein Binding
	Biological Process	Signal Transduction Protein Transport Positive Regulation Of Protein Autophosphorylation Activation Of Protein Kinase Activity Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Negative Regulation Of Mitotic Nuclear Division Regulation Of DNA Biosynthetic Process	Response To Unfolded Protein ERAD Pathway
Pathways
Drugs
Diseases
GWAS		Carotid intima media thickness x smoking interaction ( 32117412) Metabolite levels ( 23823483) Obesity-related traits ( 23251661) Photic sneeze reflex ( 27182965) Systolic blood pressure ( 34074324) Urinary albumin-to-creatinine ratio ( 32600054)	Body mass index ( 26426971) Chronotype ( 30696823)
Interacting Genes		29 interacting genes: AMFR CCDC47 CELF1 COPS7A CWF19L1 DNAJB13 FYN GLUD2 GRB2 GSN HGS HNRNPH1 MAP3K3 NDC80 NOMO1 PDPN PELP1 PHYH PIK3R1 PWP2 RAB18 TASOR TOLLIP TSG101 TUBA1B UBC UBXN4 VAV2 VCP	5 interacting genes: GNGT1 MAILR TOM1L1 UBQLN1 VCP
Entrez ID		10040	23190
HPRD ID		05266	18254
Ensembl ID		ENSG00000141198	ENSG00000144224
Uniprot IDs		O75674	Q92575
PDB IDs		3RRU	2KXJ
Enriched GO Terms of Interacting Partners?		BAT3 Complex Binding ERAD Pathway Proteolysis Involved In Protein Catabolic Process Cytosol Ubiquitin Binding Response To Endoplasmic Reticulum Stress Neurotrophin TRKA Receptor Binding Endosome Transport Via Multivesicular Body Sorting Pathway Intracellular Signaling Cassette Derlin-1 Retrotranslocation Complex Phosphotyrosine Residue Binding Multivesicular Body Sorting Pathway Intracellular Signal Transduction Multi-pass Transmembrane Protein Insertion Into ER Membrane Multi-pass Translocon Complex Ubiquitin Protein Ligase Binding SUMO Binding Catabolic Process Insulin Receptor Substrate Binding Macromolecule Catabolic Process Modification-dependent Protein Catabolic Process Transmembrane Receptor Protein Tyrosine Kinase Adaptor Activity Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Positive Regulation Of Exosomal Secretion Phosphatidylinositol 3-kinase Binding Ubiquitin-specific Protease Binding Regulation Of Exosomal Secretion Protein-folding Chaperone Binding Macromolecule Metabolic Process Proteolysis Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Regulation Of Protein Modification Process Cell Activation Protein Phosphatase Binding RNA Binding Regulation Of Post-translational Protein Modification Fc Receptor Mediated Stimulatory Signaling Pathway Ubiquitin-like Protein Ligase Binding Protein Binding Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Endoplasmic Reticulum Membrane Proteasomal Protein Catabolic Process Vascular Endothelial Growth Factor Receptor Signaling Pathway Ephrin Receptor Binding Fc-gamma Receptor Signaling Pathway Cellular Response To Glycine Response To Singlet Oxygen Epidermal Growth Factor Receptor Binding COP9 Signalosome Positive Regulation Of Cellular Component Biogenesis	Cellular Response To Oxygen Levels Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Flavin Adenine Dinucleotide Catabolic Process Positive Regulation Of Post-translational Protein Modification VCP-NSFL1C Complex Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Cellular Response To Arsenite Ion Ubiquitin-dependent Protein Catabolic Process Endoplasmic Reticulum Stress-induced Pre-emptive Quality Control Modification-dependent Protein Catabolic Process Polyubiquitin Modification-dependent Protein Binding Regulation Of Protein Modification Process Macroautophagy Autophagosome Maturation ERAD Pathway Proteolysis Involved In Protein Catabolic Process Proteasome Complex Mitotic Spindle Disassembly Positive Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Protein Modification Process Protein-containing Complex Disassembly Positive Regulation Of Oxidative Phosphorylation Positive Regulation Of Protein K63-linked Deubiquitination Negative Regulation Of Store-operated Calcium Channel Activity Negative Regulation Of Toll-like Receptor 3 Signaling Pathway Positive Regulation Of Protein Metabolic Process Cytoplasm Protein Quality Control BAT3 Complex Binding Positive Regulation Of Proteolysis Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Protein Deubiquitination Positive Regulation Of Protein Catabolic Process Stress Granule Disassembly Response To Endoplasmic Reticulum Stress Positive Regulation Of Mitochondrial Membrane Potential Aggresome Assembly Negative Regulation Of Protein Localization To Chromatin Macromolecule Catabolic Process Endosome To Lysosome Transport Via Multivesicular Body Sorting Pathway Regulation Of Post-translational Protein Modification Deubiquitinase Activator Activity Positive Regulation Of Protein Autophosphorylation Protein-DNA Covalent Cross-linking Repair Derlin-1 Retrotranslocation Complex Inclusion Body Assembly VCP-NPL4-UFD1 AAA ATPase Complex Regulation Of Protein Localization To Chromatin Response To Hypoxia K48-linked Polyubiquitin Modification-dependent Protein Binding
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