ZBTB33 and SELENOS

		ZBTB33	SELENOS
Description		zinc finger and BTB domain containing 33	selenoprotein S
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GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Plasma Membrane	Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytoplasmic Microtubule Plasma Membrane Membrane Very-low-density Lipoprotein Particle Low-density Lipoprotein Particle Derlin-1-VIMP Complex Derlin-1 Retrotranslocation Complex
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Methyl-CpG Binding Sequence-specific DNA Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding	Protein Binding Antioxidant Activity Enzyme Binding Signaling Receptor Activity ATPase Binding Ubiquitin-specific Protease Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Cytokine Production Regulation Of Immune System Process Wnt Signaling Pathway Intracellular Signal Transduction Negative Regulation Of DNA-templated Transcription	Negative Regulation Of Acute Inflammatory Response To Antigenic Stimulus Regulation Of Gluconeogenesis Intracellular Protein Transport ER Overload Response Response To Glucose Endoplasmic Reticulum Unfolded Protein Response Retrograde Protein Transport, ER To Cytosol Negative Regulation Of Interleukin-6 Production Negative Regulation Of Tumor Necrosis Factor Production Cellular Response To Insulin Stimulus Cellular Response To Oxidative Stress ERAD Pathway Establishment Of Protein Localization Cell Redox Homeostasis Negative Regulation Of Glycogen Biosynthetic Process Negative Regulation Of D-glucose Import Negative Regulation Of Inflammatory Response Response To Redox State Cellular Response To Lipopolysaccharide Regulation Of Nitric Oxide Metabolic Process Cellular Oxidant Detoxification Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Macrophage Apoptotic Process
Pathways		Negative Regulation of CDH1 Gene Transcription	E3 ubiquitin ligases ubiquitinate target proteins
Drugs
Diseases
GWAS
Interacting Genes		11 interacting genes: CBFA2T3 CTNND1 GSDMD GYS1 NCOR1 NUDT22 PLS3 SELENOS SUMO2 SUMO3 TRIM28	25 interacting genes: APOA5 BLZF1 CD180 CELF4 DERL1 EIF2AK1 ETV7 GTF2IRD1 KLHDC2 KPNB1 LIMK1 LINS1 LRRK1 MFHAS1 NCBP1 OR4F4 SAA1 SNRPA1 SRPK2 SYNM TARS3 TM2D3 TTC23 VCP ZBTB33
Entrez ID		10009	55829
HPRD ID		02269	12133
Ensembl ID		ENSG00000177485	ENSG00000131871
Uniprot IDs		Q86T24	Q6GYA4 Q9BQE4
PDB IDs		2LT7 3FKC 3M4T 3M8V 4F6M 4F6N 5VMU 5VMV 5VMW 5VMX 5VMY 5VMZ 6DF5 6DF8 6DF9 6DFA 6DFB 6DFC 6V8U	2Q2F 5KIU 5KIY 6DO4
Enriched GO Terms of Interacting Partners?		Protein Sumoylation Negative Regulation Of Glycolytic Process Regulation Of Generation Of Precursor Metabolites And Energy Protein Tag Activity SUMO Transferase Activity Negative Regulation Of D-glucose Transmembrane Transport Negative Regulation Of ATP Metabolic Process Ubiquitin-like Protein Ligase Binding Transcription Corepressor Activity Regulation Of Glycolytic Process Negative Regulation Of Blood Vessel Branching Structural Constituent Of Presynaptic Actin Cytoskeleton GDP-mannose Hydrolase Activity Regulation Of Carbohydrate Catabolic Process Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of ATP Metabolic Process Regulation Of Small Molecule Metabolic Process Regulation Of Purine Nucleotide Metabolic Process Regulation Of D-glucose Transmembrane Transport Glycogen Synthase Activity, Transferring Glucose-1-phosphate Krueppel-associated Box Domain Binding Derlin-1-VIMP Complex UDP-sugar Diphosphatase Activity Alpha-1,4-glucan Glucosyltransferase (UDP-glucose Donor) Activity Ubiquitin-like Protein Ligase Activity Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process PML Body Negative Regulation Of Small Molecule Metabolic Process Positive Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Transmembrane Transport Positive Regulation Of Protein Localization To Cell-cell Junction Embryonic Placenta Morphogenesis Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Regulation Of Protein Localization To Cell-cell Junction Presynaptic Actin Cytoskeleton Organization Actin Filament Network Formation Convergent Extension Involved In Axis Elongation Chromo Shadow Domain Binding Negative Regulation Of Acute Inflammatory Response To Antigenic Stimulus	Ubiquitin Protein Ligase Binding Spliceosomal Complex Assembly Derlin-1 Retrotranslocation Complex Cellular Response To Misfolded Protein Response To Misfolded Protein Protein-RNA Complex Assembly Retrograde Protein Transport, ER To Cytosol MHC Class I Protein Binding Ubiquitin-specific Protease Binding High-density Lipoprotein Particle Regulation Of MRNA Splicing, Via Spliceosome Alternative MRNA Splicing, Via Spliceosome Positive Regulation Of MRNA Splicing, Via Spliceosome Cellular Response To Topologically Incorrect Protein
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