SDHC

Description		succinate dehydrogenase complex subunit C
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Membrane Respiratory Chain Complex II (succinate Dehydrogenase)
	Molecular Function	Protein Binding Electron Transfer Activity Heme Binding Metal Ion Binding
	Biological Process	Tricarboxylic Acid Cycle Mitochondrial Electron Transport, Succinate To Ubiquinone Aerobic Respiration Proton Motive Force-driven Mitochondrial ATP Synthesis
Pathways		Respiratory electron transport Citric acid cycle (TCA cycle) Maturation of TCA enzymes and regulation of TCA cycle
Drugs		2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-Triol Ubiquinone Q1
Diseases
GWAS		Paclitaxel disposition in epithelial ovarian cancer ( 29367611) Visceral adipose tissue adjusted for BMI ( 22589738)
Novel Interacting Genes		6 novel interacting genes: ARHGDIA DEDD MDM2 RBFOX2 RGS4 XRCC6
Interacting Genes		6 interacting genes: ARHGDIA DEDD MDM2 RBFOX2 RGS4 XRCC6
Entrez ID		6391
HPRD ID		03878
Ensembl ID		ENSG00000143252
Uniprot IDs		A0A0S2Z4B7 A0A0S2Z4C9 A0AAQ5BHE7 Q99643
PDB IDs		8GS8
Enriched GO Terms of Interacting Partners?		Cellular Response To Gamma Radiation Rho GDP-dissociation Inhibitor Activity Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of RNA Metabolic Process Response To Gamma Radiation DNA End Binding Negative Regulation Of DNA-templated Transcription Response To Ionizing Radiation Ku70:Ku80 Complex Cellular Response To Ionizing Radiation Negative Regulation Of RNA Biosynthetic Process Response To Alkaloid Response To Vitamin B1 Response To Water-immersion Restraint Stress Response To Formaldehyde Cellular Response To Vitamin B1 Response To Cocaine Cellular Response To Actinomycin D Regulation Of Heart Rate Negative Regulation Of Glycine Import Across Plasma Membrane Negative Regulation Of Dopamine Receptor Signaling Pathway Regulation Of Smooth Muscle Cell Proliferation NEDD8 Ligase Activity Response To Actinomycin D Regulation Of Muscle Cell Differentiation Traversing Start Control Point Of Mitotic Cell Cycle Regulation Of Protein Catabolic Process At Postsynapse, Modulating Synaptic Transmission Negative Regulation Of Transcription Of Nucleolar Large RRNA By RNA Polymerase I Cellular Response To Radiation Cellular Hyperosmotic Salinity Response Protein-containing Complex DNA-dependent Protein Kinase Complex Cellular Response To UV-C Dorsal Root Ganglion Development Hyperosmotic Salinity Response Receptor Serine/threonine Kinase Binding Regulation Of Heart Contraction DNA-dependent Protein Kinase-DNA Ligase 4 Complex 5'-deoxyribose-5-phosphate Lyase Activity GTPase Activator Activity Nucleus Nucleolus Cellular Response To X-ray Negative Regulation Of Macromolecule Biosynthetic Process Nuclear Telomere Cap Complex Cellular Response To Salt Stress Double-stranded Telomeric DNA Binding Nonhomologous End Joining Complex Regulation Of Blood Circulation Atrial Septum Development
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