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FBXW5

Description F-box and WD repeat domain containing 5
Image No pdb structure
GO Annotations Cellular Component
  • Cytoplasm
  • Cytosol
  • SCF Ubiquitin Ligase Complex
  • Cul4-RING E3 Ubiquitin Ligase Complex
Molecular Function
  • Protein Binding
  • Protein Kinase Binding
Biological Process
  • Protein Polyubiquitination
  • Regulation Of Mitotic Nuclear Division
  • Regulation Of Centrosome Duplication
  • Protein Ubiquitination
  • SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
  • Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
  • Post-translational Protein Modification
Pathways
  • Association of TriC/CCT with target proteins during biosynthesis
  • Neddylation
  • Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS
  • Blood protein levels ( 29875488)
  • Heel bone mineral density ( 30598549)
  • Plateletcrit ( 32888494)
Novel Interacting Genes 1 novel interacting genes: CYP1A1
Interacting Genes 35 interacting genes: ADAMTSL4 CYSRT1 EFEMP2 FAM168A FBLN2 KRT31 KRT34 KRT37 KRT40 KRTAP1-3 KRTAP10-3 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP4-1 KRTAP4-12 KRTAP6-3 KRTAP9-3 KRTAP9-4 MDFI MID2 MTUS2 MYB NBPF19 NLK NOTCH2NLA PLEKHF2 S100B SASS6 SEC23B SKP1 TRIM27 TSC2 UBE2R2 VWC2
Entrez ID 54461
HPRD ID 10955
Ensembl ID ENSG00000159069
Uniprot IDs A0A024R8H7 Q969U6
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025