DTYMK

Description		deoxythymidylate kinase
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GO Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion Cytosol
	Molecular Function	Nucleotide Binding Nucleoside Diphosphate Kinase Activity DTMP Kinase Activity ATP Binding Kinase Activity Transferase Activity
	Biological Process	DUDP Biosynthetic Process DTDP Biosynthetic Process DTTP Biosynthetic Process Nucleotide Biosynthetic Process Thymidine Biosynthetic Process Cellular Response To Growth Factor Stimulus
Pathways		Interconversion of nucleotide di- and triphosphates
Drugs		Thymidine monophosphate 2',3'-Dideoxythymidine-5'-Monophosphate 3'-Fluoro-3'-deoxythymidine 5'-monophosphate 3'-deoxy-3'-aminothymidine monophosphate p1-(5'-adenosyl)p5-(5'-thymidyl)pentaphosphate Zidovudine monophosphate P1-(5'-Adenosyl)P5-(5'-(3'azido-3'-Deoxythymidyl))Pentaphosphate Phosphoaminophosphonic Acid-Adenylate Ester
Diseases
GWAS		Asthma ( 31959851) Diverticular disease ( 30177863) Prostate cancer ( 23535732)
Novel Interacting Genes		5 novel interacting genes: CDC20 CEBPA DHFR FZR1 HSD17B7
Interacting Genes		5 interacting genes: CDC20 CEBPA DHFR FZR1 HSD17B7
Entrez ID		1841
HPRD ID		01773
Ensembl ID		ENSG00000168393
Uniprot IDs		P23919 Q53F55 Q6FGU2
PDB IDs		1E2D 1E2E 1E2F 1E2G 1E2Q 1E98 1E99 1E9A 1E9B 1E9C 1E9D 1E9E 1E9F 1NMX 1NMY 1NMZ 1NN0 1NN1 1NN3 1NN5 2XX3
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Anaphase-promoting Complex-dependent Catabolic Process Regulation Of Anaphase-promoting Complex-dependent Catabolic Process Positive Regulation Of Ubiquitin Protein Ligase Activity Anaphase-promoting Complex Binding Ubiquitin-protein Transferase Activator Activity Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteasomal Protein Catabolic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Ubiquitin Ligase Activator Activity Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteolysis Regulation Of Proteasomal Protein Catabolic Process Anaphase-promoting Complex-dependent Catabolic Process Positive Regulation Of Protein Catabolic Process Anaphase-promoting Complex Regulation Of Ubiquitin-protein Transferase Activity Regulation Of Meiotic Nuclear Division Alcohol Metabolic Process Negative Regulation Of Cell Cycle Regulation Of Protein Catabolic Process Regulation Of Proteolysis Regulation Of Meiotic Cell Cycle Small Molecule Biosynthetic Process Small Molecule Metabolic Process Regulation Of Protein Metabolic Process Metaphase/anaphase Transition Of Meiosis I RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Response To Methotrexate Positive Regulation Of Catabolic Process Ubiquitin-like Ligase-substrate Adaptor Activity Positive Regulation Of Protein Ubiquitination Cholesterol Metabolic Process Positive Regulation Of Post-translational Protein Modification Histone Deacetylase Binding Sterol Metabolic Process Regeneration Response To Vitamin B2 C/EBP Complex Dihydrofolate Reductase Activity Regulation Of Nuclear Division CHOP-C/EBP Complex Embryonic Organ Development Dihydrofolate Metabolic Process DNA Synthesis Involved In Mitotic DNA Replication Negative Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Protein Metabolic Process Meiotic Cell Cycle Phase Transition
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