RAB31

Description		RAB31, member RAS oncogene family
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GO Annotations	Cellular Component	Phagocytic Cup Cytoplasm Endosome Early Endosome Late Endosome Golgi Apparatus Trans-Golgi Network Cytosol Plasma Membrane Endomembrane System Membrane Secretory Granule Membrane Phagocytic Vesicle Membrane Cytoplasmic Vesicle Early Endosome Membrane Trans-Golgi Network Membrane Early Phagosome Membrane Phagocytic Vesicle
	Molecular Function	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Hydrolase Activity GDP Binding
	Biological Process	Intracellular Protein Transport Endocytosis Receptor Internalization Cellular Response To Insulin Stimulus Golgi To Plasma Membrane Protein Transport Regulated Exocytosis Golgi Vesicle Transport Positive Regulation Of Phagocytosis, Engulfment Phagosome Maturation
Pathways		Neutrophil degranulation RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Age at first sexual intercourse ( 27089180) Basophil count ( 32888494) Blood pressure (age interaction) ( 24954895) Bone fracture in osteoporosis ( 28580392) Dupuytren's disease ( 28886342) Lung adenocarcinoma ( 28604730)
Novel Interacting Genes		7 novel interacting genes: ALS2CL EEA1 EGFR IRAK1 MAPK6 MPP3 OCRL
Interacting Genes		7 interacting genes: ALS2CL EEA1 EGFR IRAK1 MAPK6 MPP3 OCRL
Entrez ID		11031
HPRD ID		05751
Ensembl ID		ENSG00000168461
Uniprot IDs		Q13636
PDB IDs		2FG5
Enriched GO Terms of Interacting Partners?		Early Endosome Membrane MAPK Cascade Kinase Activity Protein Kinase Activity Epidermal Growth Factor Binding Positive Regulation Of Protein Kinase C Signaling Epidermal Growth Factor Receptor Activity Shc-EGFR Complex Multivesicular Body, Internal Vesicle Lumen Inositol Phosphate Phosphatase Activity Phosphatidylinositol Phosphate 5-phosphatase Activity Phosphatidylinositol Bisphosphate Phosphatase Activity Phosphatidylinositol Phosphate 4-phosphatase Activity Septin Cytoskeleton Postsynaptic Early Endosome Axonal Spine Chemical Synaptic Transmission, Postsynaptic Synaptic Vesicle To Endosome Fusion
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