TNFSF15 and SLC46A2

		TNFSF15	SLC46A2
Description		TNF superfamily member 15	solute carrier family 46 member 2
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane	Plasma Membrane Cell Surface Integral Component Of Membrane
	Molecular Function	Signaling Receptor Binding Cytokine Activity Tumor Necrosis Factor Receptor Binding Protein Binding	Symporter Activity
	Biological Process	Apoptotic Process Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Immune Response Signal Transduction Activation Of NF-kappaB-inducing Kinase Activity	T Cell Homeostasis Regulation Of T Cell Differentiation Thymus Development Transmembrane Transport Negative Regulation Of T Cell Apoptotic Process Positive Regulation Of Nucleotide-binding Oligomerization Domain Containing 1 Signaling Pathway
Pathways		TNFs bind their physiological receptors
Drugs
Diseases
GWAS		Asthma ( 32296059) Behcet's disease ( 33393726) Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Crohn's disease ( 18587394 30500874 21102463 32581322 26891255 23266558) Inflammatory bowel disease ( 27569725 18758464 23128233) Leprosy ( 20018961 25642632) Metabolite levels ( 23823483) Pediatric autoimmune diseases ( 26301688) Primary biliary cholangitis ( 28425483 23000144 28062665 30643196) Ulcerative colitis ( 20848476 21297633) Ulcerative colitis or Crohn's disease ( 21699788)
Interacting Genes		9 interacting genes: DELEC1 FKBP15 OAT PTBP3 SLC46A2 SRSF11 TMEM126A TNFRSF25 TNFRSF6B	1 interacting genes: TNFSF15
Entrez ID		9966	57864
HPRD ID		04956	16411
Ensembl ID		ENSG00000181634	ENSG00000119457
Uniprot IDs		A0A0U5JA19 O95150	A0A024QYV1 Q9BY10
PDB IDs		2O0O 2QE3 2RE9 2RJK 2RJL 3K51 3MI8
Enriched GO Terms of Interacting Partners?
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