SLC46A2 and TNFSF15

		SLC46A2	TNFSF15
Description		solute carrier family 46 member 2	TNF superfamily member 15
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Cell Surface Integral Component Of Membrane	Extracellular Space Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane
	Molecular Function	Symporter Activity	Signaling Receptor Binding Cytokine Activity Tumor Necrosis Factor Receptor Binding Protein Binding
	Biological Process	T Cell Homeostasis Regulation Of T Cell Differentiation Thymus Development Transmembrane Transport Negative Regulation Of T Cell Apoptotic Process Positive Regulation Of Nucleotide-binding Oligomerization Domain Containing 1 Signaling Pathway	Apoptotic Process Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Immune Response Signal Transduction Activation Of NF-kappaB-inducing Kinase Activity
Pathways			TNFs bind their physiological receptors
Drugs
Diseases
GWAS			Asthma ( 32296059) Behcet's disease ( 33393726) Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Crohn's disease ( 18587394 30500874 21102463 32581322 26891255 23266558) Inflammatory bowel disease ( 27569725 18758464 23128233) Leprosy ( 20018961 25642632) Metabolite levels ( 23823483) Pediatric autoimmune diseases ( 26301688) Primary biliary cholangitis ( 28425483 23000144 28062665 30643196) Ulcerative colitis ( 20848476 21297633) Ulcerative colitis or Crohn's disease ( 21699788)
Interacting Genes		1 interacting genes: TNFSF15	9 interacting genes: DELEC1 FKBP15 OAT PTBP3 SLC46A2 SRSF11 TMEM126A TNFRSF25 TNFRSF6B
Entrez ID		57864	9966
HPRD ID		16411	04956
Ensembl ID		ENSG00000119457	ENSG00000181634
Uniprot IDs		A0A024QYV1 Q9BY10	A0A0U5JA19 O95150
PDB IDs			2O0O 2QE3 2RE9 2RJK 2RJL 3K51 3MI8
Enriched GO Terms of Interacting Partners?
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