MAFB and ZDHHC2

Number of citations of the paper that reports this interaction (PubMedID 20211142)
361

Data Source:
BioGRID (two hybrid)

		MAFB	ZDHHC2
Description		MAF bZIP transcription factor B	zinc finger DHHC-type palmitoyltransferase 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Transcription Regulator Complex	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Plasma Membrane Integral Component Of Plasma Membrane Postsynaptic Density Recycling Endosome Membrane Postsynaptic Recycling Endosome
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Transcription Factor Binding Identical Protein Binding Sequence-specific DNA Binding Protein-containing Complex Binding	Palmitoyltransferase Activity Protein-cysteine S-myristoyltransferase Activity Protein-cysteine S-palmitoyltransferase Activity Protein Homodimerization Activity Protein-cysteine S-stearoyltransferase Activity
	Biological Process	Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Segment Specification Sensory Organ Development Respiratory Gaseous Exchange By Respiratory System Rhombomere 5 Development Rhombomere 6 Development Abducens Nerve Formation T Cell Differentiation In Thymus Brain Segmentation Inner Ear Morphogenesis Fat Cell Differentiation Regulation Of Myeloid Cell Differentiation Negative Regulation Of Erythrocyte Differentiation Negative Regulation Of Osteoclast Differentiation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Thymus Development	Protein Targeting To Membrane Synaptic Vesicle Maturation Peptidyl-L-cysteine S-palmitoylation Protein Palmitoylation Regulation Of Cell-cell Adhesion Regulation Of Protein Catabolic Process Cellular Protein Metabolic Process Regulation Of Neuronal Synaptic Plasticity Protein Localization To Plasma Membrane Positive Regulation Of Long-term Synaptic Potentiation Regulation Of Protein Localization To Plasma Membrane Protein Localization To Postsynaptic Membrane Positive Regulation Of AMPA Glutamate Receptor Clustering Positive Regulation Of Endosome To Plasma Membrane Protein Transport
Pathways		Activation of anterior HOX genes in hindbrain development during early embryogenesis	Surfactant metabolism
Drugs
Diseases
GWAS		Adult body size ( 32376654) Apolipoprotein B levels ( 32203549) Aspartate aminotransferase levels ( 33547301) Birth weight ( 31043758 27680694) Bone mineral density (hip) ( 30172743) Cholesterol, total ( 24097068 25961943 20686565) Cleft lip with or without cleft palate ( 28054174) Cognitive decline rate in late mild cognitive impairment ( 26252872) Drug-induced Stevens-Johnson syndrome or toxic epidermal necrolysis (SJS/TEN) ( 21221126) Dupuytren's disease ( 28886342 21732829) Height ( 25282103) Iron status biomarkers (ferritin levels) ( 33536631) LDL cholesterol ( 24097068 19060906 25961943 20686565) LDL cholesterol levels ( 32203549 28334899) Liver enzyme levels (alanine transaminase) ( 33972514) Liver enzyme levels (alkaline phosphatase) ( 33972514) Low density lipoprotein cholesterol levels ( 33339817) Metabolite levels (lipoprotein measures) ( 27005778) Nonsyndromic cleft lip ( 31609978) Nonsyndromic cleft lip with cleft palate ( 28232668) Nonsyndromic cleft lip with or without cleft palate ( 25775280) Obesity-related traits ( 23251661) Orofacial clefts ( 28054174) Paneth cell defects in Crohn's disease ( 28352666) Plasma parathyroid hormone levels ( 30134803) QT interval (ambient particulate matter interaction) ( 28749367) Red blood cell count ( 32888494) Response to TNF antagonist treatment ( 18615156) Serum alkaline phosphatase levels ( 33547301) Serum total protein level ( 29403010) Spleen volume ( 34128465) Total body bone mineral density ( 29304378) Total cholesterol levels ( 33339817) Triglyceride levels ( 32203549) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Diastolic blood pressure response to hydrochlorothiazide in hypertension ( 27802415) Parkinson's disease ( 32201043) Schizophrenia ( 28991256 30285260) Systolic blood pressure response to hydrochlorothiazide in hypertension ( 27802415)
Interacting Genes		12 interacting genes: ATF4 BACH1 FOS FOSL1 HOXD12 JUN KRTAP4-2 MAF STK4 ZDHHC2 ZFP64 ZWINT	2 interacting genes: MAFB MSX2
Entrez ID		9935	51201
HPRD ID		07129	15715
Ensembl ID		ENSG00000204103	ENSG00000104219
Uniprot IDs		Q9Y5Q3	A0A140VKD9 Q9UIJ5
PDB IDs
Enriched GO Terms of Interacting Partners?
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