PJA2 and MOB1A

Number of citations of the paper that reports this interaction (PubMedID 23652010)
44

Data Source:
BioGRID (affinity chromatography technology, two hybrid, pull down, unspecified method, protein complementation assay, enzymatic study)

		PJA2	MOB1A
Description		praja ring finger ubiquitin ligase 2	MOB kinase activator 1A
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Endoplasmic Reticulum Membrane Plasma Membrane Postsynaptic Density Intermediate Filament Cytoskeleton	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Extracellular Exosome
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Protein Kinase A Catalytic Subunit Binding Protein Kinase A Regulatory Subunit Binding Metal Ion Binding	Protein Binding Protein Kinase Activator Activity Metal Ion Binding
	Biological Process	Inflammatory Response Long-term Memory Regulation Of Protein Kinase A Signaling Protein Ubiquitination Positive Regulation Of Toll-like Receptor 2 Signaling Pathway Hippo Signaling Regulation Of Macrophage Activation Innate Immune Response Positive Regulation Of JNK Cascade Positive Regulation Of P38MAPK Cascade	Positive Regulation Of Protein Phosphorylation Signal Transduction Hippo Signaling
Pathways		Antigen processing: Ubiquitination & Proteasome degradation	Signaling by Hippo
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Body mass index ( 29273807) Frontotemporal dementia with GRN mutation ( 29724592) HDL cholesterol levels ( 32203549) Heel bone mineral density ( 30598549) Triglyceride levels ( 34074324)	Gestational age at birth (maternal effect) ( 28877031)
Interacting Genes		14 interacting genes: KSR1 MAGED1 MFHAS1 MOB1A PRKAR1A PRKAR2A UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2J1 UBE2L6 UBE2N UBE2W	21 interacting genes: APP CCDC85B CDK2 CMTM3 FAM118A FAM9B GMEB2 IKZF4 KANK2 KXD1 LZTFL1 MST1 PCYT1A PJA2 PTPN5 SEPTIN3 STRN3 TDO2 TMEM190 TRIM32 WASHC3
Entrez ID		9867	55233
HPRD ID		11436	14727
Ensembl ID		ENSG00000198961	ENSG00000114978
Uniprot IDs		O43164	Q9H8S9
PDB IDs			1PI1 4J1V 4JIZ 5BRK 5BRM 5TWF 5TWG 5TWH 5XQZ 6MCP 6MCQ
Enriched GO Terms of Interacting Partners?
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