MOB1A and PJA2

Number of citations of the paper that reports this interaction (PubMedID 23652010)
44

Data Source:
BioGRID (affinity chromatography technology, two hybrid, pull down, unspecified method, protein complementation assay, enzymatic study)

		MOB1A	PJA2
Description		MOB kinase activator 1A	praja ring finger ubiquitin ligase 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Extracellular Exosome	Golgi Membrane Cytoplasm Endoplasmic Reticulum Membrane Plasma Membrane Postsynaptic Density Intermediate Filament Cytoskeleton
	Molecular Function	Protein Binding Protein Kinase Activator Activity Metal Ion Binding	Ubiquitin-protein Transferase Activity Protein Binding Protein Kinase A Catalytic Subunit Binding Protein Kinase A Regulatory Subunit Binding Metal Ion Binding
	Biological Process	Positive Regulation Of Protein Phosphorylation Signal Transduction Hippo Signaling	Inflammatory Response Long-term Memory Regulation Of Protein Kinase A Signaling Protein Ubiquitination Positive Regulation Of Toll-like Receptor 2 Signaling Pathway Hippo Signaling Regulation Of Macrophage Activation Innate Immune Response Positive Regulation Of JNK Cascade Positive Regulation Of P38MAPK Cascade
Pathways		Signaling by Hippo	Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Gestational age at birth (maternal effect) ( 28877031)	Apolipoprotein A1 levels ( 32203549) Body mass index ( 29273807) Frontotemporal dementia with GRN mutation ( 29724592) HDL cholesterol levels ( 32203549) Heel bone mineral density ( 30598549) Triglyceride levels ( 34074324)
Interacting Genes		21 interacting genes: APP CCDC85B CDK2 CMTM3 FAM118A FAM9B GMEB2 IKZF4 KANK2 KXD1 LZTFL1 MST1 PCYT1A PJA2 PTPN5 SEPTIN3 STRN3 TDO2 TMEM190 TRIM32 WASHC3	14 interacting genes: KSR1 MAGED1 MFHAS1 MOB1A PRKAR1A PRKAR2A UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2J1 UBE2L6 UBE2N UBE2W
Entrez ID		55233	9867
HPRD ID		14727	11436
Ensembl ID		ENSG00000114978	ENSG00000198961
Uniprot IDs		Q9H8S9	O43164
PDB IDs		1PI1 4J1V 4JIZ 5BRK 5BRM 5TWF 5TWG 5TWH 5XQZ 6MCP 6MCQ
Enriched GO Terms of Interacting Partners?
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