SUSD6 and OTULIN

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SUSD6	OTULIN
Description		sushi domain containing 6	OTU deubiquitinase with linear linkage specificity
Image		No pdb structure
GO Annotations	Cellular Component	Cellular_component Integral Component Of Membrane	Cytoplasm Cytosol LUBAC Complex
	Molecular Function	Molecular_function Protein Binding	Thiol-dependent Deubiquitinase Protein Binding Cysteine-type Peptidase Activity
	Biological Process	Cellular Response To DNA Damage Stimulus Cell Death	Sprouting Angiogenesis Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Wnt Signaling Pathway Protein Ubiquitination Negative Regulation Of NF-kappaB Transcription Factor Activity Innate Immune Response Negative Regulation Of Inflammatory Response Regulation Of Canonical Wnt Signaling Pathway Nucleotide-binding Oligomerization Domain Containing 2 Signaling Pathway Protein Linear Deubiquitination
Pathways			Regulation of TNFR1 signaling Synthesis of active ubiquitin: roles of E1 and E2 enzymes
Drugs
Diseases
GWAS			Asthma ( 31959851 34103634 31619474) Asthma (childhood onset) ( 31036433) Cerebrospinal fluid neurofilament light levels ( 31930058)
Interacting Genes		9 interacting genes: ADAMTSL4 DCUN1D1 FAM241B KRTAP1-3 KRTAP10-8 MTURN OTULIN TMEM19 UBXN6	10 interacting genes: BCL10 DAZAP2 DVL2 FAM168A OTUD7B SFT2D1 SPART SPATA2 SUSD6 TMEM239
Entrez ID		9766	90268
HPRD ID		10010	14266
Ensembl ID		ENSG00000100647	ENSG00000154124
Uniprot IDs		Q92537	Q96BN8
PDB IDs			3ZNV 3ZNX 3ZNZ 4KSJ 4KSK 4KSL 4OYK 4P0B 5OE7 6I9C 6SAK
Enriched GO Terms of Interacting Partners?
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