CD68 and KTN1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CD68	KTN1
Description		CD68 molecule	kinectin 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Lysosome Lysosomal Membrane Plasma Membrane Membrane Integral Component Of Membrane Late Endosome Membrane Azurophil Granule Membrane	Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Integral Component Of Plasma Membrane Membrane Integral Component Of Membrane Integral Component Of Endoplasmic Reticulum Membrane
	Molecular Function	Protein Binding	RNA Binding Protein Binding Kinesin Binding Cadherin Binding
	Biological Process	Inflammatory Response To Antigenic Stimulus Negative Regulation Of Dendritic Cell Antigen Processing And Presentation Aging Cellular Response To Nutrient Levels Autocrine Signaling Cellular Response To Lipopolysaccharide Establishment Of Protein Localization To Organelle Cellular Response To Oxidised Low-density Lipoprotein Particle Stimulus	Microtubule-based Movement Protein Transport
Pathways		Neutrophil degranulation	Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) RHO GTPases activate KTN1 Post-translational protein phosphorylation RHOA GTPase cycle CDC42 GTPase cycle RAC1 GTPase cycle RHOG GTPase cycle RND3 GTPase cycle RND2 GTPase cycle
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Heel bone mineral density ( 28869591) IgA levels ( 28628107) Metabolic syndrome ( 31589552) Post bronchodilator FEV1/FVC ratio ( 26634245) Refractive error ( 32231278)	Brain morphology (MOSTest) ( 32665545) Early spontaneous preterm birth ( 31194736) Lean body mass ( 28552196) Neurofibrillary tangles ( 31497858) Plasma anti-thyroglobulin levels ( 29678681) Subcortical brain region volumes ( 25607358)
Interacting Genes		12 interacting genes: ADRB2 AGR2 AQP6 CLEC2D KTN1 MAL2 MUC1 PLEKHB2 RALGDS SGTB TMEM179B TOMM6	30 interacting genes: ABI1 BNIP3 CD3G CD68 CDC42 CLEC4C CLEC7A EEF1D FFAR2 IKBKE INPP5E KIF5B KIR2DL3 LHFPL5 M6PR MEOX2 MFSD14B PDCD1LG2 PLEKHA5 RAC1 RHOA RHOG SGTA SIRPA STOM SUSD3 SYNE4 SYNPR TMEM179B UBE2I
Entrez ID		968	3895
HPRD ID		01093	02661
Ensembl ID		ENSG00000129226	ENSG00000126777
Uniprot IDs		P34810	A0A024R663 Q86UP2
PDB IDs
Enriched GO Terms of Interacting Partners?
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