KTN1 and CD68

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		KTN1	CD68
Description		kinectin 1	CD68 molecule
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Integral Component Of Plasma Membrane Membrane Integral Component Of Membrane Integral Component Of Endoplasmic Reticulum Membrane	Lysosome Lysosomal Membrane Plasma Membrane Membrane Integral Component Of Membrane Late Endosome Membrane Azurophil Granule Membrane
	Molecular Function	RNA Binding Protein Binding Kinesin Binding Cadherin Binding	Protein Binding
	Biological Process	Microtubule-based Movement Protein Transport	Inflammatory Response To Antigenic Stimulus Negative Regulation Of Dendritic Cell Antigen Processing And Presentation Aging Cellular Response To Nutrient Levels Autocrine Signaling Cellular Response To Lipopolysaccharide Establishment Of Protein Localization To Organelle Cellular Response To Oxidised Low-density Lipoprotein Particle Stimulus
Pathways		Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) RHO GTPases activate KTN1 Post-translational protein phosphorylation RHOA GTPase cycle CDC42 GTPase cycle RAC1 GTPase cycle RHOG GTPase cycle RND3 GTPase cycle RND2 GTPase cycle	Neutrophil degranulation
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Early spontaneous preterm birth ( 31194736) Lean body mass ( 28552196) Neurofibrillary tangles ( 31497858) Plasma anti-thyroglobulin levels ( 29678681) Subcortical brain region volumes ( 25607358)	Brain morphology (MOSTest) ( 32665545) Heel bone mineral density ( 28869591) IgA levels ( 28628107) Metabolic syndrome ( 31589552) Post bronchodilator FEV1/FVC ratio ( 26634245) Refractive error ( 32231278)
Interacting Genes		30 interacting genes: ABI1 BNIP3 CD3G CD68 CDC42 CLEC4C CLEC7A EEF1D FFAR2 IKBKE INPP5E KIF5B KIR2DL3 LHFPL5 M6PR MEOX2 MFSD14B PDCD1LG2 PLEKHA5 RAC1 RHOA RHOG SGTA SIRPA STOM SUSD3 SYNE4 SYNPR TMEM179B UBE2I	12 interacting genes: ADRB2 AGR2 AQP6 CLEC2D KTN1 MAL2 MUC1 PLEKHB2 RALGDS SGTB TMEM179B TOMM6
Entrez ID		3895	968
HPRD ID		02661	01093
Ensembl ID		ENSG00000126777	ENSG00000129226
Uniprot IDs		A0A024R663 Q86UP2	P34810
PDB IDs
Enriched GO Terms of Interacting Partners?
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