EIF5B and TFCP2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		EIF5B	TFCP2
Description		eukaryotic translation initiation factor 5B	transcription factor CP2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol	Chromatin Nucleus Nucleoplasm Cytosol Protein-containing Complex
	Molecular Function	RNA Binding Translation Initiation Factor Activity GTPase Activity Protein Binding GTP Binding Metal Ion Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Transcription Factor Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Translational Initiation Regulation Of Translational Initiation	Regulation Of Transcription By RNA Polymerase II MRNA Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II
Pathways		GTP hydrolysis and joining of the 60S ribosomal subunit
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972)
Interacting Genes		11 interacting genes: BRCA1 CBL CDC42 CSNK2A1 ECT2 EIF1AX ETS1 PAXIP1 SIRPA TFCP2 ZBTB3	74 interacting genes: ACAA1 ADPRH APBB1 ASAP3 BAG6 C19orf73 CA1 CAPN3 CASP8 CBX8 CDC73 COIL DNAJC5B DPH1 E2F8 EAF1 EIF5B EPHA10 FAM120C FANCL FARS2 FBXL18 FXR2 GPANK1 HAPLN2 HDAC1 HDAC2 IRAK1BP1 LDB3 LSM1 MAPK1 MAPK14 MAPK8 MOB3C MORF4L1 MRPL11 MRPL40 MVP NABP1 NEDD9 NFE4 NHSL2 NOM1 NPEPL1 PHF1 PHF21B PIMREG PITPNM1 PLCB1 POLL POLR3GL PPIG PPP1R1B PPP3R2 PSMD5 RBMS1 RNF2 RXRB SDCBP SHTN1 SIN3A STMN2 SUMO1 TCEA2 TDRD1 TLK1 TRAPPC12 TSPAN12 UBE2I UBP1 YJU2 YY1 ZCCHC10 ZCCHC12
Entrez ID		9669	7024
HPRD ID		07304	01790
Ensembl ID		ENSG00000158417	ENSG00000135457
Uniprot IDs		O60841 Q8N5A0	A0A024R120 Q12800
PDB IDs
Enriched GO Terms of Interacting Partners?
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