BABAM2 and BABAM1

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1103

Data Source:
BioGRID (affinity chromatography technology, pull down)
HPRD (two hybrid)

		BABAM2	BABAM1
Description		BRISC and BRCA1 A complex member 2	BRISC and BRCA1 A complex member 1
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GO Annotations	Cellular Component	Nuclear Ubiquitin Ligase Complex Nucleus Nucleoplasm Cytoplasm Cytosol BRCA1-A Complex BRISC Complex	Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Body BRCA1-A Complex BRISC Complex
	Molecular Function	Peroxisome Targeting Sequence Binding Tumor Necrosis Factor Receptor Binding Protein Binding Polyubiquitin Modification-dependent Protein Binding	Protein Binding
	Biological Process	Double-strand Break Repair Chromatin Organization Apoptotic Process Cellular Response To DNA Damage Stimulus Mitotic G2 DNA Damage Checkpoint Signaling Signal Transduction Response To Ionizing Radiation Negative Regulation Of Apoptotic Process Positive Regulation Of DNA Repair Cell Division Protein K63-linked Deubiquitination	Double-strand Break Repair Chromatin Organization Mitotic G2 DNA Damage Checkpoint Signaling Response To Ionizing Radiation Positive Regulation Of DNA Repair Cell Division Protein K63-linked Deubiquitination
Pathways		Metalloprotease DUBs Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks Nonhomologous End-Joining (NHEJ) Processing of DNA double-strand break ends G2/M DNA damage checkpoint	Metalloprotease DUBs Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks Nonhomologous End-Joining (NHEJ) Processing of DNA double-strand break ends G2/M DNA damage checkpoint
Drugs
Diseases
GWAS		Blond vs. brown/black hair color ( 30531825) Estimated glomerular filtration rate ( 31152163) Intraocular pressure ( 29617998) Low density lipoprotein cholesterol levels ( 33339817) Urate levels ( 31578528) Uterine fibroids ( 31649266)	Cancer ( 27197191) Cancer (pleiotropy) ( 27197191) Epithelial ovarian cancer ( 25581431) Mitochondrial DNA copy number ( 30704525)
Interacting Genes		8 interacting genes: BABAM1 GFI1B NCOA3 SHMT2 SUMO2 UBC UBE2D1 VRK2	9 interacting genes: AKT1 BABAM2 BRCA1 GATAD2A SHMT2 TERF2IP TNKS TRIM27 UBC
Entrez ID		9577	29086
HPRD ID		08498	13702
Ensembl ID		ENSG00000158019	ENSG00000105393
Uniprot IDs		Q9NXR7	A0A024R7L2 J3KQS6 Q9NWV8
PDB IDs		6H3C 6R8F	6H3C
Enriched GO Terms of Interacting Partners?
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