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BABAM2

Description BRISC and BRCA1 A complex member 2
Image
GO Annotations Cellular Component
  • Nuclear Ubiquitin Ligase Complex
  • Nucleus
  • Nucleoplasm
  • Cytoplasm
  • Cytosol
  • BRCA1-A Complex
  • BRISC Complex
Molecular Function
  • Peroxisome Targeting Sequence Binding
  • Tumor Necrosis Factor Receptor Binding
  • Protein Binding
  • Polyubiquitin Modification-dependent Protein Binding
Biological Process
  • Double-strand Break Repair
  • Chromatin Organization
  • Apoptotic Process
  • Cellular Response To DNA Damage Stimulus
  • Mitotic G2 DNA Damage Checkpoint Signaling
  • Signal Transduction
  • Response To Ionizing Radiation
  • Negative Regulation Of Apoptotic Process
  • Positive Regulation Of DNA Repair
  • Cell Division
  • Protein K63-linked Deubiquitination
Pathways
  • Metalloprotease DUBs
  • Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
  • Nonhomologous End-Joining (NHEJ)
  • Processing of DNA double-strand break ends
  • G2/M DNA damage checkpoint
Drugs
Diseases
GWAS
  • Blond vs. brown/black hair color ( 30531825)
  • Estimated glomerular filtration rate ( 31152163)
  • Intraocular pressure ( 29617998)
  • Low density lipoprotein cholesterol levels ( 33339817)
  • Urate levels ( 31578528)
  • Uterine fibroids ( 31649266)
Interacting Genes 8 interacting genes: BABAM1 GFI1B NCOA3 SHMT2 SUMO2 UBC UBE2D1 VRK2
Entrez ID 9577
HPRD ID 08498
Ensembl ID ENSG00000158019
Uniprot IDs Q9NXR7
PDB IDs 6H3C 6R8F
Enriched GO Terms of Interacting Partners?
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