CD38 and PCDH7

		CD38	PCDH7
Description		CD38 molecule	protocadherin 7
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GO Annotations	Cellular Component	Nucleus Plasma Membrane Cell Surface Membrane Integral Component Of Membrane Basolateral Plasma Membrane Secretory Granule Membrane Extracellular Exosome	Plasma Membrane Integral Component Of Plasma Membrane Platelet Alpha Granule Membrane
	Molecular Function	NAD+ Nucleosidase Activity Transferase Activity Phosphorus-oxygen Lyase Activity Identical Protein Binding NAD(P)+ Nucleosidase Activity NAD+ Nucleotidase, Cyclic ADP-ribose Generating	Calcium Ion Binding
	Biological Process	Response To Hypoxia Signal Transduction Positive Regulation Of Cytosolic Calcium Ion Concentration Female Pregnancy Response To Xenobiotic Stimulus Negative Regulation Of Neuron Projection Development Artery Smooth Muscle Contraction NAD Metabolic Process Positive Regulation Of Cell Growth Positive Regulation Of B Cell Proliferation Positive Regulation Of Insulin Secretion Response To Estradiol Response To Retinoic Acid Response To Progesterone Response To Hydroperoxide Negative Regulation Of Apoptotic Process Negative Regulation Of Bone Resorption Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Vasoconstriction B Cell Receptor Signaling Pathway Long-term Synaptic Depression Response To Interleukin-1 Apoptotic Signaling Pathway	Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules
Pathways		Nicotinate metabolism	Platelet degranulation RHOA GTPase cycle RHOB GTPase cycle
Drugs		Daratumumab Isatuximab Mezagitamab
Diseases
GWAS		Blood protein levels ( 28240269) Neurological blood protein biomarker levels ( 31320639) Parkinson's disease ( 27182965 28892059)	Adult body size ( 32376654) Adventurousness ( 30643258) Alzheimer's disease (late onset) ( 30820047) Attention deficit hyperactivity disorder ( 32279069) Body size at age 10 ( 32376654) Depressive symptom (sleep problems) (binary trait) ( 31530331) Diastolic blood pressure x smoking status (ever vs never) interaction (1df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Diffusing capacity of carbon monoxide ( 30694715) Electroencephalogram traits ( 25387704) Epilepsy ( 25087078) General risk tolerance (MTAG) ( 30643258) Generalized epilepsy ( 30531953) Hip circumference adjusted for BMI ( 28552196) Influenza A (H1N1) infection ( 26379185) Lipid traits ( 22028671) Mean arterial pressure x educational attainment (some college) interaction (2df) ( 32372009) Menarche (age at onset) ( 25231870) Mild influenza (H1N1) infection ( 26379185) Mouth morphology (principal component model) ( 30174134) Number of sexual partners ( 30643258) Obesity-related traits ( 23251661) Refractive astigmatism ( 25367360) Refractive error ( 32231278) Response to antipsychotic treatment in schizophrenia ( 29503163) Response to ziprazidone in schizophrenia ( 29503163) Smoking status (ever vs never smokers) ( 30643258) Triglyceride levels ( 34074324) Underweight status ( 25133637) Very long-chain saturated fatty acid levels (fatty acid 22:0) ( 25378659) White matter hyperintensities in ischemic stroke ( 26674333)
Interacting Genes		7 interacting genes: CBL CD4 CD9 FCGR3A LCK PCDH7 PECAM1	9 interacting genes: BST1 CD38 MTDH PDLIM5 PPARGC1A PPP1CA RFC1 RPIA SPP1
Entrez ID		952	5099
HPRD ID		00116	04288
Ensembl ID		ENSG00000004468	ENSG00000169851
Uniprot IDs		B4E006 P28907	O60245
PDB IDs		1YH3 1ZVM 2EF1 2HCT 2I65 2I66 2I67 2O3Q 2O3R 2O3S 2O3T 2O3U 2PGJ 2PGL 3DZF 3DZG 3DZH 3DZI 3DZJ 3DZK 3F6Y 3I9M 3I9N 3OFS 3RAJ 3ROK 3ROM 3ROP 3ROQ 3U4H 3U4I 4CMH 4F45 4F46 4OGW 4TMF 4XJS 4XJT 5F1K 5F1O 5F21 6EDR 6VUA	2YST
Enriched GO Terms of Interacting Partners?
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