PCDH7 and PDLIM5

		PCDH7	PDLIM5
Description		protocadherin 7	PDZ and LIM domain 5
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GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Platelet Alpha Granule Membrane	Stress Fiber Cytosol Adherens Junction Postsynaptic Density Actin Cytoskeleton Membrane Z Disc Filamentous Actin Cell Projection Presynapse
	Molecular Function	Calcium Ion Binding	Actin Binding Protein Kinase C Binding Protein Binding Actinin Binding Metal Ion Binding Protein N-terminus Binding Muscle Alpha-actinin Binding Cadherin Binding Involved In Cell-cell Adhesion
	Biological Process	Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules	Heart Development Actin Cytoskeleton Organization Regulation Of Synapse Assembly Regulation Of Dendritic Spine Morphogenesis Cell Growth Involved In Cardiac Muscle Cell Development Muscle Structure Development Cell-cell Adhesion
Pathways		Platelet degranulation RHOA GTPase cycle RHOB GTPase cycle	Neurexins and neuroligins
Drugs
Diseases
GWAS		Adult body size ( 32376654) Adventurousness ( 30643258) Alzheimer's disease (late onset) ( 30820047) Attention deficit hyperactivity disorder ( 32279069) Body size at age 10 ( 32376654) Depressive symptom (sleep problems) (binary trait) ( 31530331) Diastolic blood pressure x smoking status (ever vs never) interaction (1df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Diffusing capacity of carbon monoxide ( 30694715) Electroencephalogram traits ( 25387704) Epilepsy ( 25087078) General risk tolerance (MTAG) ( 30643258) Generalized epilepsy ( 30531953) Hip circumference adjusted for BMI ( 28552196) Influenza A (H1N1) infection ( 26379185) Lipid traits ( 22028671) Mean arterial pressure x educational attainment (some college) interaction (2df) ( 32372009) Menarche (age at onset) ( 25231870) Mild influenza (H1N1) infection ( 26379185) Mouth morphology (principal component model) ( 30174134) Number of sexual partners ( 30643258) Obesity-related traits ( 23251661) Refractive astigmatism ( 25367360) Refractive error ( 32231278) Response to antipsychotic treatment in schizophrenia ( 29503163) Response to ziprazidone in schizophrenia ( 29503163) Smoking status (ever vs never smokers) ( 30643258) Triglyceride levels ( 34074324) Underweight status ( 25133637) Very long-chain saturated fatty acid levels (fatty acid 22:0) ( 25378659) White matter hyperintensities in ischemic stroke ( 26674333)	Asparaginase-induced acute pancreatitis in acute lymphoblastic leukemia (onset time) ( 27114598) Coronary artery disease ( 29212778) Diastolic blood pressure ( 30224653) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Lewy body disease ( 25188341) Mean platelet volume ( 32888494 27863252) Myocardial infarction ( 33532862) PR interval ( 32439900) Prostate cancer ( 19767753) Pulse pressure ( 30578418) Response to simvastatin treatment (PCSK9 protein level change) ( 25089948) Uterine fibroids ( 31649266) Visceral fat ( 22589738) Waist circumference adjusted for body mass index ( 28552196)
Interacting Genes		9 interacting genes: BST1 CD38 MTDH PDLIM5 PPARGC1A PPP1CA RFC1 RPIA SPP1	15 interacting genes: ACTB ACTN1 CACNA1B CCDC136 COIL GFI1B KRT40 KRTAP10-7 NOD2 PCDH7 PRKCB PRKCE PRKCG TRIM39 ZYX
Entrez ID		5099	10611
HPRD ID		04288	05799
Ensembl ID		ENSG00000169851	ENSG00000163110
Uniprot IDs		O60245	A0A024RDE8 B7Z481 B7Z8X5 Q96HC4
PDB IDs		2YST	2DAR 2UZC
Enriched GO Terms of Interacting Partners?
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