GGPS1 and MX1

		GGPS1	MX1
Description		geranylgeranyl diphosphate synthase 1	MX dynamin like GTPase 1
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GO Annotations	Cellular Component	Cytosol	Nucleus Cytoplasm Endoplasmic Reticulum Membrane Cytosol Microtubule Membrane Nuclear Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Dimethylallyltranstransferase Activity Farnesyltranstransferase Activity Geranyltranstransferase Activity Prenyltransferase Activity Protein Binding Identical Protein Binding Metal Ion Binding	GTPase Activity Protein Binding GTP Binding Microtubule Binding Identical Protein Binding
	Biological Process	Isoprenoid Metabolic Process Isoprenoid Biosynthetic Process Geranyl Diphosphate Biosynthetic Process Geranylgeranyl Diphosphate Biosynthetic Process Farnesyl Diphosphate Biosynthetic Process	Apoptotic Process Defense Response Signal Transduction Response To Virus Response To Type I Interferon Negative Regulation Of Viral Genome Replication Innate Immune Response Defense Response To Virus Interleukin-27-mediated Signaling Pathway Antiviral Innate Immune Response
Pathways		Cholesterol biosynthesis Activation of gene expression by SREBF (SREBP)	ISG15 antiviral mechanism Interferon alpha/beta signaling
Drugs		Pamidronic acid Zoledronic acid Ibandronate Geranyl Diphosphate Farnesyl thiopyrophosphate ISOPENTENYL PYROPHOSPHATE Minodronic acid (1-HYDROXYHEPTANE-1,1-DIYL)BIS(PHOSPHONIC ACID) (1-HYDROXYNONANE-1,1-DIYL)BIS(PHOSPHONIC ACID) (2,2-DIPHOSPHONOETHYL)(DODECYL)DIMETHYLPHOSPHONIUM [2-(3-DIBENZOFURAN-4-YL-PHENYL)-1-HYDROXY-1-PHOSPHONO-ETHYL]-PHOSPHONIC ACID Farnesyl diphosphate Geranylgeranyl diphosphate Lauryl alcohol diphosphonic acid (6E,11E)-HEPTADECA-6,11-DIENE-9,9-DIYLBIS(PHOSPHONIC ACID)
Diseases
GWAS		Asthma ( 29273806)
Interacting Genes		3 interacting genes: ATOX1 MX1 SDCBP	55 interacting genes: ACTB ADRM1 APP BLM BRD7 C7orf25 CAB39L CASP8AP2 CBX4 CCL16 CD5 CHD3 DAXX DCP2 EPM2AIP1 FANCA FXR1 GGPS1 GMEB1 GPC4 HMGXB4 KIF26B KLHL35 LRRC4B MCCD1 MX2 NDC80 NDUFV3 PDE9A PGRMC1 PIAS1 PIAS2 PLRG1 PRDX6 PSD3 PSG9 RELA SIAH1 SIRPA SLC25A3 SP100 TDG TRPC1 TRPC3 TRPC4 TRPC5 TRPC6 TRPC7 TUBA1A TUBB ZBTB16 ZCCHC12 ZFP36 ZNF251 ZNF623
Entrez ID		9453	4599
HPRD ID		06099	00919
Ensembl ID		ENSG00000152904	ENSG00000157601
Uniprot IDs		A0A024R3R2 O95749	P20591
PDB IDs		2Q80 6C56 6C57 6G31 6G32 6R4V	3LJB 3SZR 3ZYS 4P4S 4P4T 4P4U 5GTM
Enriched GO Terms of Interacting Partners?
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