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GGPS1

Description geranylgeranyl diphosphate synthase 1
Image
GO Annotations Cellular Component
  • Cytosol
Molecular Function
  • Dimethylallyltranstransferase Activity
  • Farnesyltranstransferase Activity
  • Geranyltranstransferase Activity
  • Prenyltransferase Activity
  • Protein Binding
  • Identical Protein Binding
  • Metal Ion Binding
Biological Process
  • Isoprenoid Metabolic Process
  • Isoprenoid Biosynthetic Process
  • Geranyl Diphosphate Biosynthetic Process
  • Geranylgeranyl Diphosphate Biosynthetic Process
  • Farnesyl Diphosphate Biosynthetic Process
Pathways
  • Cholesterol biosynthesis
  • Activation of gene expression by SREBF (SREBP)
Drugs
  • Pamidronic acid
  • Zoledronic acid
  • Ibandronate
  • Geranyl Diphosphate
  • Farnesyl thiopyrophosphate
  • ISOPENTENYL PYROPHOSPHATE
  • Minodronic acid
  • (1-HYDROXYHEPTANE-1,1-DIYL)BIS(PHOSPHONIC ACID)
  • (1-HYDROXYNONANE-1,1-DIYL)BIS(PHOSPHONIC ACID)
  • (2,2-DIPHOSPHONOETHYL)(DODECYL)DIMETHYLPHOSPHONIUM
  • [2-(3-DIBENZOFURAN-4-YL-PHENYL)-1-HYDROXY-1-PHOSPHONO-ETHYL]-PHOSPHONIC ACID
  • Farnesyl diphosphate
  • Geranylgeranyl diphosphate
  • Lauryl alcohol diphosphonic acid
  • (6E,11E)-HEPTADECA-6,11-DIENE-9,9-DIYLBIS(PHOSPHONIC ACID)
Diseases
GWAS
  • Asthma ( 29273806)
Interacting Genes 3 interacting genes: ATOX1 MX1 SDCBP
Entrez ID 9453
HPRD ID 06099
Ensembl ID ENSG00000152904
Uniprot IDs A0A024R3R2 O95749
PDB IDs 2Q80 6C56 6C57 6G31 6G32 6R4V
Enriched GO Terms of Interacting Partners?
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