MED23 and WDTC1

Number of citations of the paper that reports this interaction (PubMedID 12421765)
41

Data Source:
HPRD (two hybrid)

		MED23	WDTC1
Description		mediator complex subunit 23	WD and tetratricopeptide repeats 1
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GO Annotations	Cellular Component	Nucleoplasm Transcription Regulator Complex Mediator Complex	Nucleoplasm Cytoplasm Cytosol Cul4-RING E3 Ubiquitin Ligase Complex
	Molecular Function	Transcription Coactivator Activity Protein Binding	Enzyme Inhibitor Activity Protein Binding Histone Binding Histone Deacetylase Binding
	Biological Process	Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated	Negative Regulation Of Transcription By RNA Polymerase II In Utero Embryonic Development Glucose Metabolic Process Regulation Of Cell Size Protein Ubiquitination Cellular Response To Insulin Stimulus Multicellular Organism Growth Negative Regulation Of Catalytic Activity Negative Regulation Of Fatty Acid Biosynthetic Process Cellular Chemical Homeostasis
Pathways		PPARA activates gene expression Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation	Neddylation
Drugs
Diseases
GWAS		L-arginine levels ( 25245031) Type 2 diabetes ( 30054458)
Interacting Genes		16 interacting genes: CEBPB CLCN3 CTDP1 ELF3 ESR1 ESR2 ETS1 FOXJ3 MED13 MED9 NCOA6 PUM2 RELA SREBF1 VDR WDTC1	4 interacting genes: CUL4B DDB1 MED23 MED4
Entrez ID		9439	23038
HPRD ID		05436	10307
Ensembl ID		ENSG00000112282	ENSG00000142784
Uniprot IDs		Q05DL5 Q9ULK4	Q8N5D0
PDB IDs		6H02	3I7N
Enriched GO Terms of Interacting Partners?
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